Protein Alignment CG3841 and Nceh1

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001120996.1
• Gene: Nceh1 / 294930
• RGDID: 1311104
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 96/482 - (19%)
• Similarity: 148/482 - (30%)
• Gaps: 162/482 - (33%)

  Fly     9 WALLLILIGFTTAVTFIGDDPVVEL--SLGRIQ-----GDTMQSFGNKTIYAFRGIRYAQSPVGQ 66
            |.|:|:      ..||.|...|..|  |||...     ...:.|||.|:
  Rat    31 WKLMLL------DATFRGAQQVSNLIHSLGLSHHLITLNFIIISFGKKS---------------- 73

  Fly    67 LRFANPVPETSWGDEVFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFEDKFPV---MVYIHGG 128
               |...|.....|..|                    |.:::.||....:...|:   :||||||
  Rat    74 ---ARSSPRVKVTDTDF--------------------DGVEVRVFEGPPKPDEPLRRSVVYIHGG 115

  Fly   129 ANVLGSGHSSYEAGPQYLLDQ---------DVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVM 184
            ...|.|...||       .||         :.|.|:..|||                   :.||.
  Rat   116 GWALASAKISY-------YDQLCTAMAEELNAVIVSIEYRL-------------------VPQVY 154

  Fly   185 ALEWVRDHI--SHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDIDNL 247
            ..|.:.|.|  :.:...||::....:..|.:.||...|....|....:......|..|...:..|
  Rat   155 FPEQIHDVIRATKYFLQPEVLDKYKVDPGRVGVSGDSAGGNLAAALGQQFTYVESLKNKLKLQAL 219

  Fly   248 FWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYE-IDGHFLHNH--- 308
            .:....|.:...|.|..:.....|......|.      |..|    .|.||: ::...::||
  Rat   220 IYPVLQALDFNTPSYQQSMNTPILPRHVMVRY------WVDY----FKGNYDFVEAMIVNNHTSL 274

  Fly   309 ------------------PTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFV- 354
                              |:.:.|    |..|:|.:..      :|.:..|...||...||..:
  Rat   275 DVERAAALRARLDWTSLLPSSIKK----NYKPVLQTIG------DARIVKEIPQLLDAAASPLIA 329

  Fly   355 -----DYAPELFLY--RHDAQIGEKLKDFYLGDNTTEINSENIENFG-----QIFSDAYIGHGVH 407
                 ...|:.::.  .||.     |:|..:      :.::.:|:.|     ..|.|.:  ||..
  Rat   330 EQEVLQALPKTYILTCEHDV-----LRDDGI------MYAKRLESAGVNVTLDHFEDGF--HGCM 381

  Fly   408 RLVQLASHFTPVYYTRMDYVG--DQSL 432
            ......::|:....||..|..  ||:|
  Rat   382 IFTSWPTNFSVGIRTRDSYFKWLDQNL 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	90/464 (19%)
Nceh1	NP_001120996.1	Abhydrolase_3	109..381	CDD:400284	66/330 (20%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		1/1 (100%)