DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3841 and SPCC417.12

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_588289.2	Gene:	SPCC417.12 / 2539430	PomBaseID:	SPCC417.12	Length:	539	Species:	Schizosaccharomyces pombe

Alignment Length:	534	Identity:	130/534 - (24%)
Similarity:	215/534 - (40%)	Gaps:	105/534 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LGRIQGDT-MQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVV 98
            :|.:.|.| :...|.:..:.|.|||||:.|||:||:..||......|...:......:||||...
pombe    20 MGVLHGLTVLDENGKEKCHRFTGIRYAKPPVGKLRWRRPVTLEDGYDYSGDYNQFKTICPQPFYN 84

  Fly    99 SLMS----------EDCLKINVFTKSFE---DKFPVMVYIHGGANVLGSGHSSYEAGPQYL---- 146
            :..:          ||||.:|::..:.|   :.:||:.:||||...:|:.....:..||.|
pombe    85 NRKNQVRNPDFKYDEDCLFLNIWVPAGEKPAEGWPVLYFIHGGWLQVGNPLHYRQCDPQDLQADG 149

  Fly   147 LDQDVVFVAFNYRLGALGFLS----TNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIG 207
            .....:.|:..:||...|||:    ........||||.||.:.|||...||..|||:.|.:.:.|
pombe   150 SPAKFILVSPGHRLNLFGFLAGKELLEEDPKSSNFGFWDQRLGLEWTYKHIESFGGNKENIAVGG 214

  Fly   208 ISAGSMAVSLHLA----SPLSAGLFHRAILMS-GSATNHFDI-DNLFWTRKLARELGCPM-YDPT 265
            |||||.:....|.    .|.:..:..||:|:| |.:.....: ::.....:||::.|.|: ....
pombe   215 ISAGSYSALFQLIYETYHPEANQIIKRALLLSNGLSVQPKSVEESQIQFNELAQKFGIPLELSSA 279

  Fly   266 DVVECLRNETWTRIVEVCKAWETYQLVNMK---WNYEIDGHFLHNHPTELIKEGNFNK------V 321
            :.:|.||...:..:.:        .::|::   :....||.|::.:..:.|.:|.|.|      .
pombe   280 EKLEKLRAIPFQDLAD--------NILNLRLHTFRAVTDGDFVNPNTFKDIYDGTFGKRIRDSGR 336

  Fly   322 PLLISFTANEFDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEIN 386
            .|:|....||....||.:.....  .|..:...:|.||        ::.:.|.:.|......|..
pombe   337 ELIIGEVNNEHSIYANTNPPKSK--EDLFNQVNNYYPE--------KVTKALLELYPKVPDMEDE 391

  Fly   387 SENIEN----FGQIFSDAYIGHG----VHRLVQLASHFTPVYYTRMDYVG--------DQSLSAP 435
            .|.:..    ||.|.||..:...    ::.||:.......:|..|:.:.|        .:||
pombe   392 KEYLAAIKALFGSIVSDMQVYASTRVLINGLVKGGVPLEKIYRYRIAFRGKFFDKYEPPESL--- 453

  Fly   436 LNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERL---TSWFTHFAK---TGTPLNST 494
                     |.||.||     |.|:     .|..|..:.|.:   .:|...:.:   ||    .|
pombe   454 ---------VPHAGDL-----GLWF-----YNVVDGILPEEIPIYKAWLKSYGEWMSTG----KT 495

  Fly   495 DIWPPCNSTVLKML 508
            | |....:...::|
pombe   496 D-WGTTKTEEYRLL 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	130/534 (24%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	43/133 (32%)
SPCC417.12	NP_588289.2	PnbA	20..534	CDD:225181	130/534 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43142
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1741
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.990