Protein Alignment CG3841 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 637
• Identity: 174/637 - (27%)
• Similarity: 262/637 - (41%)
• Gaps: 164/637 - (25%)

  Fly    12 LLILIGFTTAVTFIGDD---PVVELSLGRIQGDTM----QSFGNKTIYAFRGIRYAQSPVGQLRF 69
            |.:.:||.:.|......   |.|....|:::|..:    :..|  .:..:.|:.||..|:|:.||
Mouse    19 LCLTLGFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILG--PVDQYLGVPYAAPPIGEKRF 81

  Fly    70 ANPVPETSWGDEVFNATSDSLVCPQ------PGV----------------VSLMSEDCLKINVFT 112
            ..|.|..||.. :.|||....||||      |.|                :...:||||.:||:.
Mouse    82 LPPEPPPSWSG-IRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYV 145

  Fly   113 ---------KSFED----------------KFPVMVYIHGGANVLGSGH-------SSYEAGPQY 145
                     |..||                ..|||||||||:.:.|:|:       :||
Mouse   146 PTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASY------ 204

  Fly   146 LLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISA 210
               .:|:.:..|||:|.||||||.....|||:|.|||:.||.||.::|:.|||||..:|:.|...
Mouse   205 ---GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGI 266

  Fly   211 GSMAVSLHLASPLSAGLFHRAILMSGSATNHFDID--NLFWTRKLARELGCPMYDPTDVVECLRN 273
            |:..|||...|..|.|||.|||:.||||.:.:.::  .:.:|..||.::||.:.|..|:|:|||.
Mouse   267 GASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQ 331

  Fly   274 ETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANE------- 331
            ::...:||.......|   ::.:...|||..:.:.|..|:::|.|....:::.....|
Mouse   332 KSAKELVEQDIQPARY---HVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEG 393

  Fly   332 ------------FDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQ-IGEKLKDFYLGDNTT 383
                        |||:              .|||||   .|:.|..... :.|.:|..|    |.
Mouse   394 VVDPEDGVSGTDFDYS--------------VSNFVD---NLYGYPEGKDTLRETIKFMY----TD 437

  Fly   384 EINSENIE----NFGQIFSDAYIGHGVHRLVQ--------LASHFTPVYYTRMDYVGDQSLSAPL 436
            ..:.:|.|    ....:|:|       |:.|:        .|.:.:|.|:... |...|||..|.
Mouse   438 WADRDNPETRRKTLVALFTD-------HQWVEPSVVTADLHARYGSPTYFYAF-YHHCQSLMKPA 494

  Fly   437 NGENKPVGVGHADDLHYVLPGYWYGP--LMAANDS--DVFMMERLTSWFTHFAKTGTPLNSTD-- 495
            ..:     ..|.|::.||......||  |...|.|  ||.:...:.:::|:|||||.|.....
Mouse   495 WSD-----AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQD 554

  Fly   496 --------------IWPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFP 533
                          .|...|......|:.|:..:|.....:.:.|.|..|.|
Mouse   555 TKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	167/615 (27%)
		Aes	<116..>235	CDD:223730	57/141 (40%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	167/610 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		3/20 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832437
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740