DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and Cel

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_058693.2	Gene:	Cel / 24254	RGDID:	2331	Length:	612	Species:	Rattus norvegicus

Alignment Length:	513	Identity:	149/513 - (29%)
Similarity:	215/513 - (41%)	Gaps:	104/513 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GRIQG--DTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVV 98
            |.::|  ..:...|..::..|:||.:|.:..    ..||.....| .....||.....|.|..:.
  Rat    31 GFVEGVNKKLSLLGGDSVDIFKGIPFATAKT----LENPQRHPGW-QGTLKATDFKKRCLQATIT 90

  Fly    99 ---SLMSEDCLKINVFT----KSFEDKFPVMVYIHGGANVLGSGHSS-------YEAGPQYLLDQ 149
               :...||||.:|::.    |......||||:|:|||.::|||..:       |: |.:.....
  Rat    91 QDDTYGQEDCLYLNIWVPQGRKQVSHDLPVMVWIYGGAFLMGSGQGANFLKNYLYD-GEEIATRG 154

  Fly   150 DVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMA 214
            :|:.|.||||:|.||||||..:...||||..||.||:.||:.:|:.|||||:.:||.|.|||:.:
  Rat   155 NVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAAS 219

  Fly   215 VSLHLASPLSAGLFHRAILMSGSATNHFDIDN--LFWTRKLARELGCPMYDPTDVVECLRNETWT 277
            |||...||.:.||..|||..||.|.:.:.|..  |||.:.:|:::|||..|...:..||
  Rat   220 VSLQTLSPYNKGLIRRAISQSGVALSPWAIQENPLFWAKTIAKKVGCPTEDTAKMAGCL------ 278

  Fly   278 RIVEVCKAWETYQLVNMKWNYEI----------DGHFLHNHPTELIKEGNFNKVPLLISFTANEF 332
            :|.:.......|:|......|.|          ||.|:.:.|..|..             .|.:.
  Rat   279 KITDPRALTLAYRLPLKSQEYPIVHYLAFIPVVDGDFIPDDPINLYD-------------NAADI 330

  Fly   333 DYNANVHLENQHLLHDFASNFVDYA----PELFLYR----HDAQIGEK----LKDFYLGDNTTEI 385
            ||.|.::..:.||........:|.|    .|...||    |....|.|    ..|.|......:.
  Rat   331 DYLAGINDMDGHLFATVDVPAIDKAKQDVTEEDFYRLVSGHTVAKGLKGTQATFDIYTESWAQDP 395

  Fly   386 NSENIENFGQIFSD----------AYIGHGVH-----RLVQLASHFT--PVYYTRMDYVGDQSLS 433
            :.||::.....|..          |...|..|     ....|.||.:  |:|
  Rat   396 SQENMKKTVVAFETDILFLIPTEMALAQHRAHAKSAKTYSYLFSHPSRMPIY------------- 447

  Fly   434 APLNGENKPVGVGHADDLHYVLPGYWYGPL-MAANDSDVFMMERLTSWFTHFAKTGTP 490
                  .|.:|..|||||.||....:..|| ..|.|..|  .:.:.:::|:|||:|.|
  Rat   448 ------PKWMGADHADDLQYVFGKPFATPLGYRAQDRTV--SKAMIAYWTNFAKSGDP 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	149/513 (29%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	58/125 (46%)
Cel	NP_058693.2	COesterase	26..542	CDD:278561	149/513 (29%)
		Aes	<118..>247	CDD:223730	61/129 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	553..612
		4 X 11 AA tandem repeats, O-glycosylated region	556..599
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740