Protein Alignment CG3841 and Ces4a

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 571
• Identity: 175/571 - (30%)
• Similarity: 264/571 - (46%)
• Gaps: 63/571 - (11%)

  Fly     5 FQLTWALLLILIGFTTAVTFIG----DDPVVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVG 65
            :.:.|.|.|.|.......|.:|    .:|::....|.:||..:. .|:..|..|.||.:::.|||
Mouse     6 WNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVH-VGDTPIQVFLGIPFSKPPVG 69

  Fly    66 QLRFANPVPETSWGDEVFNATSDSLVCPQPG---VVSL------------MSEDCLKINVFTKSF 115
            ..|||.|.|...| :.:.:||:....|.|..   ::|:            .|||||.:||:....
Mouse    70 TRRFAPPEPPLPW-NGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVL 133

  Fly   116 ---EDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNF 177
               ....||||:..|||.:.||. |:|| |.:......||.|...||||.|||.||.:|..:||:
Mouse   134 APGAPLLPVMVWFPGGAFLAGSA-STYE-GSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNW 196

  Fly   178 GFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHF 242
            |.|||:.||.||:::|..|||||:.||:.|.|||:|:||..:.|||:.||||:||..||:|....
Mouse   197 GLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKA 261

  Fly   243 DI--DNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEI----- 300
            .|  |.|...:|:|...||.......:|||||:.:...:..|.|....:|..:.|...||
Mouse   262 FITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLS 326

  Fly   301 ---DGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLE---NQHLLHDFASNFVDYAPE 359
               ||......|..|:..|....||.|:.....||::|....::   ||.:::....|.:.::..
Mouse   327 PVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFN 391

  Fly   360 LFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHG--VHRLVQLASHF----TP 418
            :.|.....|:....:: ||.|   .|::.:.:.|.....| .||..  |:..:|.|.:.    :|
Mouse   392 VLLNITKEQVPVVARE-YLND---AISNHDWKMFRNRLID-LIGDATFVYATLQAARYHRDAGSP 451

  Fly   419 VY-YTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFT 482
            || |....:.....:..|.||.:      |.|:|.|:. |..:....:|.:...|.::.:..| .
Mouse   452 VYLYEFKHHASSGIIIKPYNGAD------HGDELSYLF-GSPFSKGSSAGEEKEFSLQMMKYW-A 508

  Fly   483 HFAKTGTPLNSTDI--WPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKL 531
            :||.||.| |...:  ||..:... |.|.....|:||......:.|.|.:|
Mouse   509 NFAHTGNP-NGEKLPYWPRFDKDE-KYLQLDFDTRVGVKLKEKKMAFWSQL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	167/540 (31%)
Ces4a	NP_666325.2	COesterase	33..554	CDD:395084	167/539 (31%)