Protein Alignment CG3841 and Ces2c

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_663578.1
• Gene: Ces2c / 234671
• MGIID: 2385905
• Length: 561
• Species: Mus musculus
• Alignment Length: 578
• Identity: 173/578 - (29%)
• Similarity: 270/578 - (46%)
• Gaps: 92/578 - (15%)

  Fly     9 WALLLILIGFTTAVTFIGDD-----PVVELSLGRIQGDTMQSFGNKT-IYAFRGIRYAQSPVGQL 67
            :.|||:||...      |.|     |:.....|:|||..:.....|. ::.|.||.:|:.|||.|
Mouse    15 FGLLLLLIHVQ------GQDSPEANPIRNTHTGQIQGSLIHVKDTKAGVHTFLGIPFAKPPVGPL 73

  Fly    68 RFANPVPETSWGDEVFNATSDSLVCPQ----------PGVVSL-----MSEDCLKINVFTKSFE- 116
            |||.|.....|.. |.:.|:...:|.|          |.:..:     ||||||.:|::|.:..
Mouse    74 RFAPPEAPEPWSG-VRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFPMSEDCLYLNIYTPAHAH 137

  Fly   117 --DKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGF 179
              ...||||:|||||.|:|.  :|...|....:::|:|.|...||||.|||.||.....:||:|:
Mouse   138 EGSNLPVMVWIHGGALVIGM--ASMFDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDQHARGNWGY 200

  Fly   180 LDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSG-------- 236
            |||..||.||:.:|:||||:|:.|||.|.|||..:||.|:.||:|.||||.||:.||
Mouse   201 LDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVALLPDLI 265

  Fly   237 SATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEID 301
            |.|:.      ..:..:|:..||...|...:|.|||.::...|:.:.|.::....|       :|
Mouse   266 SETSE------MVSTTVAKLSGCEAMDSQALVRCLRGKSEAEILAINKVFKMIPAV-------VD 317

  Fly   302 GHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLL-----HDFASNFVDYAPELF 361
            |.|...||.||:...:|:.||.:|....:||.::..|.:.:..::     .:..:...|.|.::.
Mouse   318 GEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQMIKGITRENLQAVLKDTAVQMM 382

  Fly   362 LYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQLASHF----TPVYYT 422
            |   ..:..:.|.:.|:|| |.:..:..|: |.::..|...   |...:|:| ||    .|||:.
Mouse   383 L---PPECSDLLMEEYMGD-TEDAQTLQIQ-FTEMMGDFMF---VIPALQVA-HFQRSHAPVYFY 438

  Fly   423 RM----DYVGDQSLSAPLNGENKP--VGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWF 481
            ..    .|..|.          :|  |...|||::.:|...:::|..:...:.:..:..|:..::
Mouse   439 EFQHPPSYFKDV----------RPPHVKADHADEIPFVFASFFWGMKLDFTEEEELLSRRMMKYW 493

  Fly   482 THFAKTGTPLNSTDI--WPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFPTAAQ 537
            .:||:.|.| ||..:  ||..:... :.|...:...||....:.|...|.|..|...|
Mouse   494 ANFARHGNP-NSEGLPYWPVMDHDE-QYLQLDIQPAVGRALKAGRLQFWTKTLPQKIQ 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	163/549 (30%)
Ces2c	NP_663578.1	COesterase	32..540	CDD:395084	162/544 (30%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561