Protein Alignment CG3841 and NLGN4Y

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001352513.1
• Gene: NLGN4Y / 22829
• HGNCID: 15529
• Length: 836
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 184/651 - (28%)
• Similarity: 277/651 - (42%)
• Gaps: 166/651 - (25%)

  Fly     7 LTWALLL-----------ILIGFTT-AVTFIGDD-----PVVELSLGRIQG--DTMQSFGNKTIY 52
            |.|..||           :|:..|. |:.|...|     |||..:.|:|||  ..:.|.....:.
Human     7 LLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVE 71

  Fly    53 AFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQ-----------------PGVVSL 100
            .:.|:.||..|.|:.||..|...:|| ..:.|||..|.||||                 ..:.:|
Human    72 QYLGVPYASPPTGERRFQPPESPSSW-TGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTL 135

  Fly   101 M------SEDCLKINVFT---------KSFED-----------------KFPVMVYIHGGANVLG 133
            |      :||||.:|::.         ::.:|                 |.|||||||||:.:.|
Human   136 MTYVQDQNEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIHEQNSKKPVMVYIHGGSYMEG 200

  Fly   134 SGH-------SSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRD 191
            :|:       :||         .:|:.:..|||||.||||||.....|||:|.|||:.||.|:.:
Human   201 TGNMIDGSILASY---------GNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEE 256

  Fly   192 HISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDID--NLFWTRKLA 254
            ::..|||||:.|||.|..||:..|||...|..|.|||.:||:.||:|.:.:.::  ...:||.||
Human   257 NVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILA 321

  Fly   255 RELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFN 319
            .::||.|.|.||:||||:|:.:..:::......||.:.   :...|||..:.:.|..|:::|.|.
Human   322 DKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIA---FGPVIDGDVIPDDPQILMEQGEFL 383

  Fly   320 KVPLLI-------------------SFTANEFDYNANVHLENQHLLHDFASNFVDYAPELFLYRH 365
            ...:::                   ..|.|:||::              .|||||   .|:.|..
Human   384 NYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFS--------------VSNFVD---NLYGYPE 431

  Fly   366 DAQ-IGEKLKDFYLGDNTTEINSENIE----NFGQIFSD-AYIGHGVHRLVQLASHFTPVYYTRM 424
            ... :.|.:|..|    |...:.||.|    ....:|:| .::...|......|.:.:|.|:...
Human   432 GKDTLRETIKFMY----TDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAF 492

  Fly   425 DYVGDQSLSAPLNGENKP--VGVGHADDLHYVLPGYWYGP--LMAANDS--DVFMMERLTSWFTH 483
             |...||       |.||  ....|.|::.||......||  |.:.|.|  ||.:...:.:::|:
Human   493 -YHHCQS-------EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 549

  Fly   484 FAKTGTPLNSTD----------------IWPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLF 532
            |||||.|.....                .|...|......|:.|:..:|.....:.:.|.|.:|.
Human   550 FAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELV 614

  Fly   533 P 533
            |
Human   615 P 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	173/612 (28%)
		Aes	<116..>235	CDD:223730	58/142 (41%)
NLGN4Y	NP_001352513.1	COesterase	46..610	CDD:306613	172/605 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840