Protein Alignment CG3841 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 636
• Identity: 172/636 - (27%)
• Similarity: 257/636 - (40%)
• Gaps: 166/636 - (26%)

  Fly    28 DPVVELSLGRIQGDTMQSFGNK---TIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDS 89
            ||:|..:.|:|:| ..:...|:   .:..|.|:.||..|.|:.||..|.|.:.|.| :.|||..:
Mouse    52 DPLVTTNFGKIRG-IKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSD-IRNATQFA 114

  Fly    90 LVCPQ-------PGV----------------VSLMSEDCLKINVF-------------------- 111
            .||||       |.|                |...|||||.:|::
Mouse   115 PVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKK 179

  Fly   112 --------TKSFEDKF------------------PVMVYIHGGANVLGSGH-------SSYEAGP 143
                    ||...|..                  |||||||||:.:.|:|:       :||
Mouse   180 ICRKGGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASY---- 240

  Fly   144 QYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGI 208
                 .:|:.:..|||||.||||||.....|||:|.||.:.||.|..::|..|||||..:|:.|.
Mouse   241 -----GNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 300

  Fly   209 SAGSMAVSLHLASPLS---------AGLFHRAILMSGSATNHFDIDNLF----WTRKLARELGCP 260
            .||...|:|...|..|         .|||.|||..||:|.:.:.:.  |    :.|.||.::||.
Mouse   301 GAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVS--FQPAKYARILATKVGCN 363

  Fly   261 MYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLL- 324
            :.|..::||||:.:.:..:|:.......|.:.   :...|||..:.:.|..|:::|.|....::
Mouse   364 VSDTVELVECLQKKPYKELVDQDVQPARYHIA---FGPVIDGDVIPDDPQILMEQGEFLNYDIML 425

  Fly   325 -------ISFTANEFDYNANVHLENQHLLHDFA-SNFVDYAPELFLYRHDAQIGEKLKDFYLGDN 381
                   :.|..|..|.:..|...:    .||| |||||   .|:.|.....:..:...|...|.
Mouse   426 GVNQGEGLKFVENIVDSDDGVSASD----FDFAVSNFVD---NLYGYPEGKDVLRETIKFMYTDW 483

  Fly   382 TTEINSE-NIENFGQIFSDAYIGHGVHRLV-------QLASHF-TPVYYTRMDYVGDQSLSAPLN 437
            ....|.| ..:....:|:|       |:.|       .|.|:| :|.|:... |...|:...|..
Mouse   484 ADRHNPETRRKTLLALFTD-------HQWVAPAVATADLHSNFGSPTYFYAF-YHHCQTDQVPAW 540

  Fly   438 GENKPVGVGHADDLHYVLPGYWYGP--LMAANDS--DVFMMERLTSWFTHFAKTGTPLNSTD--- 495
            .:     ..|.|::.|||.....||  |...|.|  ||.:...:.:::|:|||||.|.....
Mouse   541 AD-----AAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDT 600

  Fly   496 -------------IWPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFP 533
                         .|...:......|:.|:..:|.....:|:..:|.:|.|
Mouse   601 KFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	169/629 (27%)
		Aes	<116..>235	CDD:223730	55/152 (36%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	168/628 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740