Protein Alignment CG3841 and cest-3

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 128/549 - (23%)
• Similarity: 222/549 - (40%)
• Gaps: 134/549 - (24%)

  Fly    30 VVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQ 94
            ::..:.|:::|.|:    |...:.|:.:.:|:.|:|:|||:.|.....| ..:.|||..|..|..
 Worm    23 IISTTYGKLEGKTV----NVDQHMFKNVPFAKPPLGKLRFSLPEWTNPW-KNIRNATEYSPSCFS 82

  Fly    95 PGVVSL------MSEDCLKINVFTKSF---EDKFPVMVYIHGGA-NVLGSGHSSYEAGPQYLLD- 148
            ...:..      ||||||.:||||..:   ......:||.|||. |:    .|:.:....::|:
 Worm    83 NSSMRTDSNFFPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINM----DSAVQFNDTFILER 143

  Fly   149 ---QDVVFVAFNYRLGALGFLSTNSSE-TKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGIS 209
               ::|||:...||||..|.|...|:. ...|....|..:||.::...||:|||..:.:.::|.|
 Worm   144 YVKENVVFIIPAYRLGIFGLLYFGSNNLVPQNLAIHDCELALRFIHQEISNFGGHKDDINLMGHS 208

  Fly   210 AGS-----MAVSLHLASPLSAGLFHRAILMSGSATNHFDIDNLFWTR--KLARELGCPMYD---- 263
            ||:     ...|.|: .| ...|.:|.|::  |....:|:..|....  ..|..:||...:
 Worm   209 AGAHISLIFGFSRHI-DP-DHKLINRIIVL--SPVPSYDMPELLIKNCYDFAERVGCYKRNVTAR 269

  Fly   264 PTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFT 328
            .|::|:|||.:....::.:.:..|..:|  ..||:.....|::...:....:....|..:||..|
 Worm   270 DTEIVKCLRKKDARGLMSMQRLMENDRL--YFWNFLAGEPFMYRDESIADFKEYAVKRDMLIGNT 332

  Fly   329 ANEFDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENF 393
            .:|..:. .:..||..:    |.:|:|       :.:..::..|. :||  .::..:|| ..|:|
 Worm   333 VDEVKWK-RLKKENPAI----AGSFMD-------WENPYEVAHKF-NFY--HDSAPVNS-TYESF 381

  Fly   394 GQ-IF--------SDAYIGHGVHRL---VQLASHFTPVYYTRMDYVGDQSLSAPLNGENKPVGVG 446
            .| ||        :.|..|..|:..   .|.:||.:.:.|    :||.
 Worm   382 TQGIFVSTATYAEAQANAGGTVYLFQSNQQPSSHVSDMQY----FVGT----------------- 425

  Fly   447 HADDLHYVLPGYWYGPLMAANDSDVFMMERLTS-WFTHFAKTGTPLNSTDIWPPCNSTVLKMLYN 510
            |.:|.|               .||:.:|:...| ...:|.|.|:|   :.:|.|.
 Worm   426 HREDYH---------------TSDMDIMDTFYSKMIVNFTKFGSP---SPVWEPL---------- 462

  Fly   511 GVVTQVGSPGYSNRYA--------VWDKL 531
                   .|...|.||        :|.::
 Worm   463 -------VPSRMNYYALEVNTEKGIWPRM 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	127/544 (23%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	128/549 (23%)