Protein Alignment CG3841 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 152/594 - (25%)
• Similarity: 249/594 - (41%)
• Gaps: 109/594 - (18%)

  Fly    31 VELSLGRIQGDTMQS----FGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLV 91
            |:||.|.|:|..:.|    |||::..||.||.|.:.|:|.|||..|.|:.:|.. |.........
 Worm    21 VQLSTGIIEGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSG-VLETKKFKPA 84

  Fly    92 C--------PQPGVVSLMSEDCLKINVFTKSF--EDK-FPVMVYIHGGANVLGSGHS-SYEAGPQ 144
            |        ...|:...:|||||.:||.|..:  |:| ..|::.:|||..:..|..: ::|....
 Worm    85 CMSNSTKTYKNGGIGGPISEDCLYLNVLTNQYCLENKNCSVVIIVHGGGYLFESAATFNHEILVN 149

  Fly   145 YLLDQD--VVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIG 207
            ..:.||  :|.|..|||||..||...|..|...|.|..|.:.|::|||..|..|||:.:.:|:.|
 Worm   150 NFVGQDRNIVVVTINYRLGIFGFGHLNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKDRITLAG 214

  Fly   208 ISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDIDNLFWTRKLARELGC----------PMY 262
            .|||:..|:....|||:.||.|:.|:|||..||.....|......:|..:||          |.:
 Worm   215 HSAGAGVVAAFTISPLTKGLIHQQIVMSGPMTNMSKKSNFKGMTAMAERVGCHSKKYGFNKLPEH 279

  Fly   263 DPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNY---EIDGHFLHNHPTELIKEGNFNKVPLL 324
            :...|..|||.:....:::.    :.:.|.|..:.:   .:||.|:.::|..|..|.:...:..|
 Worm   280 EVEQVYSCLRKKPAQELLDA----QLWLLQNSTFYFGAPPVDGEFITDYPDNLYSEKSIFSINTL 340

  Fly   325 ISFTANEFD---YNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEIN 386
            :..|..|..   |.:|.:.........|..|..|.. .:.:|:.......|.:.:|:..:.::..
 Worm   341 LGTTTRELQDTGYISNSNYSKFETKETFLKNLCDQI-GIEIYKESEDFSSKCQKWYINGSDSKSL 404

  Fly   387 SENIENFGQ----------------IFSDAYIGHGVHRLVQLASHFTPVYYTRMDYVGDQSLSAP 435
            |:::|.:.|                ::|.||.|.|            |.:...|      .:.:|
 Worm   405 SDDMEFYTQAINLADAHARKGKKVYMYSYAYSGAG------------PAFKKYM------KVKSP 451

  Fly   436 LNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTS-WFTHFAKTGTPLNSTD---- 495
                      .|::||.|.. |...| :.|..|   :::|.:.| .|..|.....|..|||
 Worm   452 ----------HHSEDLIYTF-GTHRG-VFAPKD---YVIEYIYSGMFADFINFEDPSPSTDQPWL 501

  Fly   496 IWPPCNSTVLKMLYNGVVTQVGSPG-----YSNRYAVWDKLFPTAAQGGGAALKLSFAVAIATGV 555
            .:...|.....:.::..:|.   ||     |:..|..|.    ||.|   .:.|..::.::.|.:
 Worm   502 QYTKENKEYFLVDFDQNLTM---PGMKKNYYAKAYEFWS----TAGQ---KSFKEEWSPSLDTFI 556

  Fly   556 ASRLIGKLM 564
            .:.|:..::
 Worm   557 ITNLVAPII 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	145/556 (26%)
		Aes	<116..>235	CDD:223730	45/122 (37%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	145/556 (26%)
		Aes	<125..>250	CDD:223730	48/124 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740