DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and ges-1

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_503411.1	Gene:	ges-1 / 178633	WormBaseID:	WBGene00001578	Length:	562	Species:	Caenorhabditis elegans

Alignment Length:	563	Identity:	163/563 - (28%)
Similarity:	258/563 - (45%)	Gaps:	102/563 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PVVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVC- 92
            |:||.:.|:::|...:.     ...|..|.:|:.||..|||..||....| ::|:.||.....|
Worm    18 PIVETNYGKVEGIEYEG-----AEVFLAIPFAKPPVDDLRFEKPVAPDPW-EDVYPATQYRNDCT 76

  Fly    93 PQPGVVSLMS----EDCLKINVFTKSFEDKFPVMVYIHGGANVLGS-GHSSYEAGPQYLLDQDVV 152
            |...:|:..|    ||||.:|:......:|.||:.:||||...:|| ....||...:....|.|:
Worm    77 PHYRLVAQFSSYSGEDCLTLNIIKPKKAEKLPVLFWIHGGGYEIGSASQHGYEFFAKRYASQGVI 141

  Fly   153 FVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSL 217
            .....||||.:||.|..:|:.:||:|..||..|||:|:.:|.:|||||..:||.|.|||:.:||.
Worm   142 VATVQYRLGFMGFFSEGTSDVQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYSAGAASVSQ 206

  Fly   218 HLASPLSAGLFHRAILMSGS-----ATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWT 277
            ...||.:...:.:||:||.|     ||....::.   :::||..||||.   ....||::.::..
Worm   207 LTMSPYTRDSYSKAIIMSASSFVGWATGPNVVET---SKQLAEILGCPW---PGAKECMKKKSLH 265

  Fly   278 RI---VEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVH 339
            .|   :|| :.|.|..:..::|:..|||.|:..:|.|||||....  |.||..:..|..|.|.::
Worm   266 EIFDAIEV-QGWTTGTIDILRWSPVIDGDFMTKNPEELIKESPVK--PTLIGMSNKEGSYFAALN 327

  Fly   340 LENQHLLHDFASNFVD-------YAPEL----FLYRHDAQIGEK-------LKDFYLGD----NT 382
            :  ..::.||..:..|       :..|:    .||.:  :.||.       :.|||:..    ..
Worm   328 M--GRVIADFGLSPEDMPKVDEEFISEIIGRKLLYNN--RYGENREKVWNDILDFYVKQGKPAEV 388

  Fly   383 TEINSENIENFGQIFSDAYIGHGVHRLVQLASHF---TPVYYTRMD---------YVGDQSLSAP 435
            .::|...::.:.::.||  |...|..|.::.|..   |||:..|||         ::.:|:..:|
Worm   389 KDLNGFYVDRYSELLSD--ITFNVPILREITSRVERKTPVWTYRMDHYDKNIWKKHIPEQARGSP 451

  Fly   436 LNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTH--------FAKTGTPLN 492
                       ||::.||:..    .|:||..|    |.:...||..:        |||||.|..
Worm   452 -----------HANEYHYLFD----MPVMAKID----MKKEPDSWIQNDLIDMVISFAKTGVPQI 497

  Fly   493 STDIWPPCNS----TVLKMLYNGVVTQVGSPGYSNRYAVWDKL 531
            ....|.|.:.    ..|.:..:||..:.|.  :....|.|::|
Worm   498 EDVEWRPVSDPDDVNFLNIRSDGVSIEHGL--FQEPLAFWNEL 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	161/558 (29%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	48/119 (40%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	161/558 (29%)
ges-1	NP_503411.1	Aes	<100..>211	CDD:223730	44/110 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810