DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3841 and clt

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_536784.1	Gene:	clt / 117300	FlyBaseID:	FBgn0000326	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	159/516 - (30%)
Similarity:	239/516 - (46%)	Gaps:	91/516 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 AFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVVSLM----------SEDCLK 107
            :|.|:.||:.|||:|||.:|.|.     |.|.  ...|.|.:.|.||..          |||||.
  Fly    44 SFLGVPYAEPPVGELRFRSPRPL-----ERFQ--KQELDCSKEGNVSYQRDPFTLEVAGSEDCLF 101

  Fly   108 INVF---TKSFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTN 169
            :||:   .||.....||||:||||....|:|:|.:.. |..|::|:|:.|..|||||||||||..
  Fly   102 LNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHF-PAKLMEQEVIVVTLNYRLGALGFLSLP 165

  Fly   170 SSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILM 234
            .....||.|..||.:|||||:::|:.|.|||..||:.|.|||..:|.||..:..:..|||:||:.
  Fly   166 EEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQ 230

  Fly   235 SGSATNHFDIDNLFW---------TRKLARELGCPMY--DPTDVVECLRNETWTRIVEVCKAWET 288
            ||:|       |:.|         ||:||..||...:  |...::..|::|         ||..|
  Fly   231 SGTA-------NMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSE---------KATPT 279

  Fly   289 YQLVNMKWNYEID--------------------GHFLHNHPTELI-KEGNFNKVPLLISFTANEF 332
            ..|.|.......|                    ..||.....||: |:.....:|:::.:.:.|
  Fly   280 AILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAE- 343

  Fly   333 DYNANVHLENQHLLHDFASNFVDYAPELFLYRHDA----QIGEKLKDFYLGDNTTEINSENIENF 393
              ...:.::.:..|..:..:.....|...:....|    :....::.|:.  |...::.||::|.
  Fly   344 --GLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFF--NGQALSKENMDNL 404

  Fly   394 GQIFSDAYIGHGVHRLVQL-ASHFT--PVYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVL 455
            ..:|||.:....:.|.|:: ||..|  |:|:.|:||||.::|...:.......||.||||:.|:.
  Fly   405 VDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLF 469

  Fly   456 PGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPLNSTDIWPPCNSTVLKMLYNGVVTQV 516
              ...|.....|..|:.:.|||...:.:||:.|.|   :.||.|     :|..:||...|:
  Fly   470 --QMAGDETEMNRDDLMVTERLCEMWANFARDGKP---SPIWKP-----VKKPHNGEPIQL 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	159/516 (31%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	56/118 (47%)
clt	NP_536784.1	COesterase	22..543	CDD:278561	159/516 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	7	6.860