Protein Alignment CG3841 and Ache

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 623
• Identity: 169/623 - (27%)
• Similarity: 262/623 - (42%)
• Gaps: 163/623 - (26%)

  Fly     5 FQLTWALLLILIGFTTAVTFIGDDP--VVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQL 67
            |.|.:.||.:|.|...|..  .:||  :|.:..|:::|..:::.|. .:.||.||.:|:.|||..
Mouse    15 FPLLFLLLSLLGGGARAEG--REDPQLLVRVRGGQLRGIRLKAPGG-PVSAFLGIPFAEPPVGSR 76

  Fly    68 RFANPVPETSWGDEVFNATSDSLVCPQ------PGVVSL--------MSEDCLKINVFT--KSFE 116
            ||..|.|:..|.. |.:||:...||.|      ||....        :|||||.:||:|  ....
Mouse    77 RFMPPEPKRPWSG-VLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPA 140

  Fly   117 DKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLS-TNSSETKGNFGFL 180
            ...||:::|:||....|:.......|......:..|.|:.|||:|..|||: ..|.|..||.|.|
Mouse   141 SPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLL 205

  Fly   181 DQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDID 245
            ||.:||:||:::|:.|||||..||:.|.|||:.:|.:|:.|..|..|||||:|.||:....:...
Mouse   206 DQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATV 270

  Fly   246 NLFWTRK----LARELGCPM----YDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNY---- 298
            :....|:    |||.:|||.    .:.|:::.|||    ||..:        .||:.:|:.
Mouse   271 SAGEARRRATLLARLVGCPPGGAGGNDTELIACLR----TRPAQ--------DLVDHEWHVLPQE 323

  Fly   299 ---------EIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFV 354
                     .:||.||.:.|..||..|:|..:.:|:....:|..|                  |:
Mouse   324 SIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSY------------------FL 370

  Fly   355 DYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQLASHFTPV 419
            .|....|           .||           :|::.:..|..:...|  ||.:...||:....:
Mouse   371 VYGVPGF-----------SKD-----------NESLISRAQFLAGVRI--GVPQASDLAAEAVVL 411

  Fly   420 YYTRMDY----------------VGDQSLSAP---LNG--------------ENKP--------V 443
            :||  |:                |||.::..|   |.|              |::.        :
Mouse   412 HYT--DWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWM 474

  Fly   444 GVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPLNSTDI----WPPCNSTV 504
            ||.|..::.::. |....|.:.....:....:||..::|:||:||.|.:..|.    |||..:..
Mouse   475 GVPHGYEIEFIF-GLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAA 538

  Fly   505 -------LKML--YNGVVTQVGSPGYSNRYAVWDKLFP 533
                   ||.|  ..|:..|.        .|.|::..|
Mouse   539 QQYVSLNLKPLEVRRGLRAQT--------CAFWNRFLP 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	160/594 (27%)
		Aes	<116..>235	CDD:223730	50/119 (42%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	159/592 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840