Protein Alignment CG3841 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 177/607 - (29%)
• Similarity: 263/607 - (43%)
• Gaps: 138/607 - (22%)

  Fly     3 RFFQLTWALLLILIGFTTAVTFIGDDPVVELSLGRIQGD--TMQSFGNKTIYAFRGIRYAQSPVG 65
            |.:.|.|    :.:...||..:....|||....|::.|.  .::.|. :.:..|.||.:|:.|:|
  Rat     2 RLYPLVW----LFLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFA-QPVAVFLGIPFAKPPLG 61

  Fly    66 QLRFANPVPETSWGDEVFNATSDSLVCPQPGV---------------VSL-MSEDCLKINVFTK- 113
            .||||.|.|...| :.|.|.||...:|.|..|               :.| .|||||.:||:|.
  Rat    62 SLRFAPPQPAEPW-NFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPA 125

  Fly   114 --SFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGN 176
              :...:.||||:||||..|:| |.|:|: |......::||.|...||||..||.||....::||
  Rat   126 DLTKNSRLPVMVWIHGGGLVVG-GASTYD-GQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGN 188

  Fly   177 FGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSG----S 237
            :|.||||.||.||:|:|::|||:|..|||.|.|||..:||..:.|||:..||||||..||    |
  Rat   189 WGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTS 253

  Fly   238 A---TNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQ---LVNMKW 296
            |   |:...|.||     :|...||.......:|.|||.:|...::|.......::   |.|.|.
  Rat   254 ALITTDSKPIANL-----IATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKE 313

  Fly   297 NYE-----IDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFVDY 356
            :|.     |||..|...|.|::.|.:||.||.::.....||.:                     .
  Rat   314 SYPFLPTVIDGVVLPKTPEEILTEKSFNTVPYIVGINKQEFGW---------------------I 357

  Fly   357 APELFLY-RHDAQIGEKLKDFYLGDN--TTEINSENI-----ENFG---------QIFSD--AYI 402
            .|.|..| ..:.::.:|.....|..:  |.:|:.:.|     :.||         .:|.|  |.:
  Rat   358 IPTLMGYPLSEGKLDQKTAKSLLWKSYPTLKISEKMIPVVAEKYFGGTDDPAKRKDLFQDLVADV 422

  Fly   403 GHGVHRLVQLASH---FTPVYYTRMDY-------------VGDQSLSAPLNGENKPVGVGHADDL 451
            ..||..::...||   ..|.:....:|             :||                 |.|:|
  Rat   423 MFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGD-----------------HGDEL 470

  Fly   452 HYVLPGYWYG-PLM--AANDSDVFMMERLTSWFTHFAKTGTPLNSTDI--WPPCNST--VLKMLY 509
            ..|     :| |.:  .|::.:..:.:.:..::.:||:.|:| |...:  ||..:..  .||:
  Rat   471 FSV-----FGSPFLKDGASEEETNLSKMVMKYWANFARNGSP-NGGGLPHWPEYDQKEGYLKI-- 527

  Fly   510 NGVVTQVGSPGYSNRYAVWDKL 531
             |..||..........|.|.:|
  Rat   528 -GASTQAAQRLKDKEVAFWSEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	170/578 (29%)
		Aes	<116..>235	CDD:223730	60/118 (51%)
Ces1d	NP_579829.3	COesterase	24..545	CDD:278561	170/576 (30%)
		Aes	<121..>239	CDD:223730	56/119 (47%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336153
Domainoid	1	1.000	232	1.000	Domainoid score	I2325
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3341
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.890