Protein Alignment CG3841 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 598
• Identity: 165/598 - (27%)
• Similarity: 257/598 - (42%)
• Gaps: 128/598 - (21%)

  Fly     9 WALLLILIGFTTAVTFIGDDPVVELSLGRIQGDTMQSFG-NKTIYAFRGIRYAQSPVGQLRFANP 72
            :.|:.:.:...||..:....|||....|::.|..:...| .:.:..|.|:.:|:.|:|.||||.|
Mouse     4 YPLIWLSLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPP 68

  Fly    73 VPETSWGDEVFNATSDSLVCPQPGV---------------VSL-MSEDCLKINVFTK---SFEDK 118
            .|...| ..|.|.||...:|.|..|               :.| .|||||.:|::|.   :...:
Mouse    69 QPAEPW-SFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSR 132

  Fly   119 FPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQV 183
            .||||:||||..|:| |.|:|: |......::||.|...||||..||.||....::||:|.||||
Mouse   133 LPVMVWIHGGGLVVG-GASTYD-GLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

  Fly   184 MALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSG----SATNHFDI 244
            .||.||:|:|::|||:|..|||.|.|||..:||:.:.|||:..||||||..||    :|....|:
Mouse   196 AALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDV 260

  Fly   245 DNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQ---LVNMKWNYE-----ID 301
            ..:  ...:|...||.......:|.|||.:|...::|.......::   |.|.|.:|.     ||
Mouse   261 KPI--AGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVID 323

  Fly   302 GHFLHNHPTELIKEGNFNKVPLLISFTANEFDY------------------NANVHLENQHLLHD 348
            |..|...|.|::.|.:|:.||.::.....||.:                  .||..|...:....
Mouse   324 GVVLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTLK 388

  Fly   349 FASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSD--AYIGHGVHRLVQ 411
            .:.|.:..            :.||    |||      .::::.....:|.|  |.:..||..::.
Mouse   389 ISENMIPV------------VAEK----YLG------GTDDLTKKKDLFQDLMADVVFGVPSVIV 431

  Fly   412 LASH-------------FTPVYYTRM---DYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWY 460
            ..||             :.|.:.:.|   ..:||                 |.|::..|     :
Mouse   432 SRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGD-----------------HGDEIFSV-----F 474

  Fly   461 G-PLM--AANDSDVFMMERLTSWFTHFAKTGTPLNSTDI--WPPCNST--VLKMLYNGVVTQVGS 518
            | |.:  .|::.:..:.:.:..::.:||:.|.| |...:  ||..:..  .||:   |..||...
Mouse   475 GSPFLKDGASEEETNLSKMVMKFWANFARNGNP-NGGGLPHWPEYDQKEGYLKI---GASTQAAQ 535

  Fly   519 PGYSNRYAVWDKL 531
            .......:.|.:|
Mouse   536 RLKDKEVSFWAEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	160/575 (28%)
		Aes	<116..>235	CDD:223730	60/118 (51%)
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	160/573 (28%)
		Aes	<121..>239	CDD:223730	55/119 (46%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790