Protein Alignment CG3841 and Ces2a

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 570
• Identity: 170/570 - (29%)
• Similarity: 273/570 - (47%)
• Gaps: 73/570 - (12%)

  Fly     9 WALLLILIGFTTAVTFI-GDD---PVVELSLGRIQGDTMQSFGNKT-IYAFRGIRYAQSPVGQLR 68
            | |.::..|....:..: |.|   |:.....|:::|..:.....|: ::||.||.:|:.|||.||
Mouse     9 W-LCVVACGLLLLLQHVHGQDSASPIRNTHRGQVRGSFVHVKDTKSGVHAFLGIPFAKPPVGLLR 72

  Fly    69 FANPVPETSWGDEVFNATSDSLVCPQPGVVSL--------------MSEDCLKINVFTKSFEDK- 118
            ||.|.....|.. |.:.||...:|.||.:::|              ||||||.:|::|.:...:
Mouse    73 FAPPEDPEPWSG-VRDGTSQPAMCLQPDIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEG 136

  Fly   119 --FPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLD 181
              .||||:||||..|:||  :|.....:....:::|.||..||||.|||.||.....:||:|:||
Mouse   137 SNLPVMVWIHGGGLVVGS--ASMNDVSKLAATEEIVIVAIQYRLGVLGFFSTGDQHARGNWGYLD 199

  Fly   182 QVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNH---FD 243
            ||.||.||:.:|::|||:.:.|||.|:|||..:||.|:.||:|.||||.||:.||.|...   .|
Mouse   200 QVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISD 264

  Fly   244 IDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNH 308
            ...:.: :.:|...||...|...::.|||.::...|:.:.:.::....|       :||.||..|
Mouse   265 TSEVVY-KTVANLSGCEATDSEALIHCLRAKSKQEILAINQVFKMIPAV-------VDGEFLPKH 321

  Fly   309 PTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFV-----DYAPELFLYRHDAQ 368
            |.||:...:|:.||.:|....:|..:...:.:...|::.:.....:     :.|..:.|   ..:
Mouse   322 PQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITRETLPAVLKNTAARMML---PPE 383

  Fly   369 IGEKLKDFYLGDNTTEINSENIE-NFGQIFSDAYIGHGVHRLVQLASHF----TPVYYTRMDYVG 428
            ....|.:.|:||  || :.|.:: .|.::..|...   |...:|:| ||    .|||:...
Mouse   384 CSHLLVEEYMGD--TE-DPETLQAQFREMLGDFMF---VIPALQVA-HFQRSQAPVYFYEF---- 437

  Fly   429 DQSLSAPLNGENKP--VGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPL 491
             |.||:.:. ..:|  |...|.||:.:|...|.:...:...:.:..:...:..::.:||:.|.|
Mouse   438 -QHLSSFIK-HVRPSHVKADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYWANFARNGNP- 499

  Fly   492 NSTDI--WPPCNSTVLKMLYNGVVTQ--VGSPGYSNRYAVWDKLFPTAAQ 537
            ||..:  ||..:.   ...|..:.||  ||....:.|...|.|..|...|
Mouse   500 NSEGLPSWPVLDH---DEQYLQLDTQPAVGRALKARRLQFWTKTLPQKIQ 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	162/540 (30%)
		Aes	<116..>235	CDD:223730	58/121 (48%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	161/537 (30%)
		Aes	<127..>230	CDD:223730	46/104 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832747
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.790