DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and tg

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001316486.1	Gene:	tg / 100492021	XenbaseID:	XB-GENE-6073495	Length:	2780	Species:	Xenopus tropicalis

Alignment Length:	565	Identity:	150/565 - (26%)
Similarity:	238/565 - (42%)	Gaps:	112/565 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPG----VVSLMSEDCLKIN 109
            |.:..|.||.||..|||..||:.|.| .:|..| :|||.....|.|||    ..|.:.||||.:|
Frog  2239 KNVVQFLGIPYAAPPVGVYRFSPPQP-VNWTGE-WNATYSRASCLQPGDGKAQYSSVGEDCLYLN 2301

  Fly   110 VFTKSFE-DKFPVMVYIHGGANVLGSGHSSYEAGPQYLLD-------QDVVFVAFNYRLGALGFL 166
            ||..... ....|::|.|       :..|.|....|..:|       .::|.|...||:|..|||
Frog  2302 VFVPQHAGTNAAVLLYFH-------NSPSDYSEKGQTFIDGSYLAAIGNIVVVTAGYRVGVFGFL 2359

  Fly   167 STNSSET--KGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFH 229
            | |:.||  .||:|.||||.||:||:::|::|||||.|::|....||:...|:|...| ...||.
Frog  2360 S-NTGETAPSGNWGLLDQVAALKWVQENIAYFGGDPTLISIAADRAGADISSIHTIVP-EGKLFR 2422

  Fly   230 RAILMSGSATNHFDIDNLFWTRK----LARELGCPMYDPTDVVECLR-------NETWTRIVEVC 283
            ||:||.|||.:...:.:....::    ||.|:.|...: .|::.|||       |...|:::...
Frog  2423 RALLMGGSAFSPMMVTSEKRAKEQVEFLAAEVECSSSN-KDLLTCLRGVDAGALNAAQTKLLAQR 2486

  Fly   284 KAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFD-----YNANVHLENQ 343
            ..::|       |...:|..::...|:.::|:..|.|:.|||.  ::|.|     ..|....|..
Frog  2487 GPFQT-------WGPIVDKLYVKETPSRMLKQKKFQKIDLLIG--SSELDGLISRAKAIKRFEET 2542

  Fly   344 HLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVH- 407
            ....|..:.:......|.....::.:.|....||    :.|.:|::...|.:....|...|.:.
Frog  2543 QGRVDKTAFYQALQNSLGGVEANSLLQEAAVWFY----SLEHSSDDYTGFSKALEKATRDHFIAC 2603

  Fly   408 RLVQLASHFTP-----VYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYGPLMAAN 467
            .::::|.|:..     :|   :.:|.| :||...:|.:.|..|..|           :|.....|
Frog  2604 PVIKMAKHWAENSKGNIY---LYHVPD-TLSQSSSGLDLPEDVIRA-----------FGLPFHTN 2653

  Fly   468 DSDVFMME------RLTSWFTHFAKTGTP----------LNSTDIWP----PCNSTVLKMLYNGV 512
            ..:.|..|      ::..:.::|.:||.|          ......||    ..|.|..|...:.:
Frog  2654 YKNQFSSEEQILSLKIMQYVSNFVRTGNPNFPYKFLRRISKELPAWPMYLAHSNGTNYKEFSSSL 2718

  Fly   513 VTQVGSPGYSNRYAVWDKLFPTAAQGGGAALKLSFAVAIATGVAS 557
            ....|..  ::..:.|:...||        ||:|      ||:.|
Frog  2719 TNNQGLK--NSECSFWNDYIPT--------LKVS------TGLKS 2747

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	141/534 (26%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	48/128 (38%)
tg	NP_001316486.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910