Protein Alignment gcm and GCM1

DIOPT Version :9

• Sequence 1: NP_001260292.1
• Gene: gcm / 34277
• FlyBaseID: FBgn0014179
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_016866879.1
• Gene: GCM1 / 8521
• HGNCID: 4197
• Length: 498
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 153/493 - (31%)
• Similarity: 231/493 - (46%)
• Gaps: 107/493 - (21%)

  Fly    26 TKSRVAIDWDINDSKMP-SVGEFDDFNDWSNGHCRLIYSVQSDEARKHASGWAMRNTNNHNVNIL 89
            ::.:..:.|||||.|:| :|.:.|.|.:|.:.:.:.|||.:...|::|.|.||||||||||..||
Human    70 SEDKEILSWDINDVKLPQNVKKTDWFQEWPDSYAKHIYSSEDKNAQRHLSSWAMRNTNNHNSRIL 134

  Fly    90 KKSCLGVLLCSAKCKLPNGASVHLRPAICDKARRKQQGKQCPNRNCNGRLEIQACRGHCGYPVTH 154
            |||||||::|...|....|..::||||||||||:|||.|:||  ||:|.|::..||||.|:|||:
Human   135 KKSCLGVVVCGRDCLAEEGRKIYLRPAICDKARQKQQRKRCP--NCDGPLKLIPCRGHGGFPVTN 197

  Fly   155 FWRRDGNGIYFQAKGTHDHPRPEAKGSTEARRLLAGGRRVRSLAVMLARESALSDKLSSLRPTKR 219
            |||.||..|:||:||.||||:||.|...||||.:   ::|.:      ..|::|..|      |.
Human   198 FWRHDGRFIFFQSKGEHDHPKPETKLEAEARRAM---KKVNT------APSSVSLSL------KG 247

  Fly   220 QAKTQSIQESKRRRMGASDVLETKQELVVPPTTY---LPTSTPTHST-----NFNQSQGSYVPAG 276
            ..:|:|: ..:.:..|:..:..:.||.|..|.:|   |..:||..::     :|::|.|.   .|
Human   248 STETRSL-PGETQSQGSLPLTWSFQEGVQLPGSYSGHLIANTPQQNSLNDCFSFSKSYGL---GG 308

  Fly   277 QGSVISQWN----------REIH----YETED--PCYANGMYSYDMLHSPLSAHSSTGSYYQENK 325
            ...:..|.:          |::.    |.:.|  |..|:|:||.   |..|.|.|...:..:.:
Human   309 ITDLTDQTSTVDPMKLYEKRKLSSSRTYSSGDLLPPSASGVYSD---HGDLQAWSKNAALGRNH- 369

  Fly   326 PQQLQHSQYQQQLSPQQHVPVSYDPSQPISSSLQCGMPSYEICDDTSSLTSSSGYCSEDYGYYNG 390
               |..:.|.....|....|.|:.|||..|......:|    .:..::.|.    |...:
Human   370 ---LADNCYSNYPFPLTSWPCSFSPSQNSSEPFYQQLP----LEPPAAKTG----CPPLW----- 418

  Fly   391 YLPNSLDVSNGSQSQNLSQDASFYTTSSEIFSVFESTLNGGGTSGVDLIYDEATAYQQHQQQGTF 455
              ||        .:.||.::        ::...|.|             |.::.||...|:.
Human   419 --PN--------PAGNLYEE--------KVHVDFNS-------------YVQSPAYHSPQED--- 449

  Fly   456 PHLTNYQQEPQDQMQSADYYYSNTGVDNSWNIQMDATY 493
            |.|..|...|..|       ||.....:.|:.:.:.||
Human   450 PFLFTYASHPHQQ-------YSLPSKSSKWDFEEEMTY 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gcm	NP_001260292.1	GCM	47..186	CDD:281598	78/138 (57%)
GCM1	XP_016866879.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145948
Domainoid	1	1.000	208	1.000	Domainoid score	I2859
eggNOG	1	0.900	-	-		E1_28MJ9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003094
OrthoInspector	1	1.000	-	-		mtm8555
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12414
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4583
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.830