DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mtpalpha and ECHDC1

DIOPT Version :9

Sequence 1:NP_609299.1 Gene:Mtpalpha / 34276 FlyBaseID:FBgn0028479 Length:783 Species:Drosophila melanogaster
Sequence 2:NP_001132982.1 Gene:ECHDC1 / 55862 HGNCID:21489 Length:307 Species:Homo sapiens


Alignment Length:316 Identity:67/316 - (21%)
Similarity:129/316 - (40%) Gaps:75/316 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 NGVLVIKIDSPNAKVNSL-GSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEAC 121
            ||:.::.:::| :::|:. |..:....|:|| :|| |......:::.|....|.:|:|:..:::.
Human    62 NGIGILTLNNP-SRMNAFSGVMMLQLLEKVI-ELE-NWTEGKGLIVRGAKNTFSSGSDLNAVKSL 123

  Fly   122 QTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVM 186
            .|.|:...:....|....|..|.....||.:.|..||||.|...||.:|:.|.:||.:....|  
Human   124 GTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE-- 186

  Fly   187 LGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYL 251
            :|::|..|||.||           :|:.|                                    
Human   187 MGIIPSWGGTTRL-----------VEIIG------------------------------------ 204

  Fly   252 EKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPLKI 316
            .:.|::|    .||.|:::.:.:..:..::..:..:|  :.|..:.|::.:.:...|    |.::
Human   205 SRQALKV----LSGALKLDSKNALNIGMVEEVLQSSD--ETKSLEEAQEWLKQFIQG----PPEV 259

  Fly   317 LDVIRAGVDKGTDAGYEA----ERKGFGELSATPESKGLIALFRGQTECKKNRFGK 368
            :..::..|..|.:...|.    ||...|.:...|.:...||        ||.:|.|
Human   260 IRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA--------KKGKFNK 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MtpalphaNP_609299.1 fa_ox_alpha_mit 38..775 CDD:131494 67/316 (21%)
crotonase-like 52..235 CDD:119339 44/177 (25%)
3HCDH_N 375..553 CDD:280833
3HCDH 556..651 CDD:279114
3HCDH 689..768 CDD:279114
ECHDC1NP_001132982.1 crotonase-like 60..251 CDD:119339 52/246 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1024
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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