DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and echdc1

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001315065.1	Gene:	echdc1 / 553585	ZFINID:	ZDB-GENE-050522-370	Length:	302	Species:	Danio rerio

Alignment Length:	350	Identity:	82/350 - (23%)
Similarity:	138/350 - (39%)	Gaps:	74/350 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SAVGQISRQQLLQNKCTRALPISAQLLQRRRLMSTNPAPVANKHLHTKVVNGVLVIKIDSPNAKV 72
            |||.:|.:|       .||....:.:..|.:|::   .|..:..|.....:|:.|:.:.:| |::
Zfish    17 SAVRKILQQ-------NRAFCSGSSVGIREKLLA---FPGGSVELQKLQESGIAVLTVSNP-ARM 70

  Fly    73 NSLGSEVSDEFERVIKDLE--TNPAVNSAVLISGKPGCFVAGADIGMLEACQTAEEATLISHGAQ 135
            |:....:..|.|:.:.:||  |.   ..||::.|..|.|.:|:|:..:.|.....:...:....|
Zfish    71 NAFSGCMMLELEQRVNELEIWTE---GKAVIVQGAAGNFCSGSDLNAVRAIANPHDGMKMCEFMQ 132

  Fly   136 VMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLP 200
            ....|:.|.....||.:.|..||||.||..||.:|:.|.|:  .:......:||:||.||..||.
Zfish   133 NTLARLLRLPLISVALVEGRALGGGAELTTACDFRLMTSDA--VIQFVHKHMGLVPGWGGAARLV 195

  Fly   201 KLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQVANDLASG 265
            .:.....||.:....::|..|..|::|:||                  |.|:.::       ..|
Zfish   196 GIIGSRNALKLLSGARKVDPDYGKQMGLVD------------------EVLQCSS-------GEG 235

  Fly   266 KLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPL--KILDVIRAGVDKGT 328
            |...:.|.           ....|:|.                  |||:  .|..|:.:|.:...
Zfish   236 KALAHAEH-----------WIAPFIKG------------------PAPVIQAIKKVVVSGRELSL 271

  Fly   329 DAGYEAERKGFGELSATPESKGLIA 353
            |...:.||..||.:...|.:...:|
Zfish   272 DEALKCERSVFGTVWGGPANLEALA 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	73/319 (23%)
		crotonase-like	52..235	CDD:119339	52/184 (28%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
echdc1	NP_001315065.1	crotonase-like	55..244	CDD:119339	56/230 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910