DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mtpalpha and CG5044

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_732020.2	Gene:	CG5044 / 41869	FlyBaseID:	FBgn0038326	Length:	386	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	57/198 - (28%)
Similarity:	93/198 - (46%)	Gaps:	34/198 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LMSTNPAPVA-------NKHLHTKVVNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAV 96
            :..|.|..:|       :..|.|:..|..::| ::.|.| :|::..|:   ..::.|.|:.....
  Fly    28 ISQTKPTTMALSVRQSSSSVLATESSNKGMII-LNRPKA-LNAINLEM---VRKIYKHLKKCEKS 87

  Fly    97 NSAVLISGK-PGCFVAGADI-GMLEACQTAEEATLISHGAQVMFDRMERS--------KKPIVAA 151
            .|.|:|.|. ...|.||.|: .::||..|.|..:         |.|.|.|        |.|.:|.
  Fly    88 KSLVIIKGTGDKAFCAGGDVRALVEAGPTDESKS---------FFREEYSTNALIGNYKIPYIAI 143

  Fly   152 ISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLPKLTSVPTALDMELTGK 216
            |.|:.:|||:.|::...||:|:  .:|...:||..:||.|..||:..||:|.. ...|.:.|||.
  Fly   144 IDGITMGGGVGLSVHGKYRVAS--DRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGY 205

  Fly   217 QVR 219
            ::|
  Fly   206 RLR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	57/198 (29%)
		crotonase-like	52..235	CDD:119339	54/178 (30%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	54/182 (30%)
CG5044	NP_732020.2	ECH_2	56..374	CDD:292731	51/170 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810