DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and CG4594

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001260305.1	Gene:	CG4594 / 34316	FlyBaseID:	FBgn0032161	Length:	280	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	76/294 - (25%)
Similarity:	117/294 - (39%)	Gaps:	69/294 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RLMSTNPAPVANKHLHTKVVN---GVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSA 99
            |||||     |.| |.|..:|   |:..:.::.|  .|||...::..:.:..|.::|.|.: ...
  Fly    17 RLMST-----ATK-LTTVEINDKTGIATLTMNRP--PVNSQNVQLLLDLQTSISEIENNKS-RGL 72

  Fly   100 VLISGKPGCFVAGADIGMLEACQT-AEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLEL 163
            :|.|.....|.||.||  .|...| .|....:....|.::..:..:..|..|||:|....||..|
  Fly    73 ILTSASSNVFSAGLDI--FEMYNTDVERLRTVWTELQNVWIALYGTTLPTAAAINGHAPAGGCLL 135

  Fly   164 ALACHYRIATKDSKTKLGLPEVMLGL-----LPGGGGTVRLPKLTSVPTALDMELT-GKQVRADR 222
            |.||.||:...:  ..:||.|..||:     |..|..:: |||..:     :..|| |:......
  Fly   136 ATACEYRVMRPN--FLIGLNEAQLGIIAPKWLMSGFASI-LPKRVA-----ERALTQGRMFTTQE 192

  Fly   223 AKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQV-----ANDLASGKLRVN------------ 270
            |..:|::|.:.           .:..|.|||.|..:     .|.||.|..::.
  Fly   193 AFEVGLIDEIA-----------SSKEEALEKCAAFIGTFAKVNPLARGLTKLQFRGDNIKEFEMI 246

  Fly   271 REK----------SGLVSKIQSFVMDTDFVKNKI 294
            |||          |..|.|:....::.  :|||:
  Fly   247 REKDIADFVALASSPGVQKVMGAYLEN--LKNKV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	76/294 (26%)
		crotonase-like	52..235	CDD:119339	51/192 (27%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
CG4594	NP_001260305.1	crotonase-like	35..275	CDD:304874	63/265 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810