DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and CG4598

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	76/318 - (23%)
Similarity:	122/318 - (38%)	Gaps:	87/318 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RLMSTNPAPVANKHLHTKVVN---GVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSA 99
            |:|||     |.| |.|..||   |:..:.::.|  .||.|..|:..:.:..|.::|:|.: ...
  Fly    17 RMMST-----ATK-LTTVEVNDKTGIATLTMNRP--PVNGLNLELLQDLKSSIDEIESNKS-RGL 72

  Fly   100 VLISGKPGCFVAGADI--------GMLEACQT-AEEATLISHGAQVMFDRMERSKKPIVAAISGV 155
            :|.|.....|.||.||        ..:.|..| .::..|..:|:.|          |..|||:|.
  Fly    73 ILTSSSSTIFSAGLDILEMYKPDKDRIRAFWTQLQDTWLALYGSSV----------PTAAAINGH 127

  Fly   156 CLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLPK--LTSVPTALDMELT---- 214
            ...||..||.:|.||:...:  ..:||.|..||::        .|:  :.|..:.|...:.
  Fly   128 SPAGGCLLATSCEYRVMVPN--FTIGLNETQLGIV--------APQWFMASFLSVLPQRIAERAL 182

  Fly   215 --GKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQV-----ANDLASGKLRVNRE 272
              |:....:.|.::|::|           ....|..|.:||....:     .|.||..
  Fly   183 NQGRMFTTEEALKVGLID-----------ETANNKEEAIEKCVAFIGTFAKVNPLARS------- 229

  Fly   273 KSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLY----PAPLKILDVIRAGVDK 326
                ::|.|....|...::|     .||:.|:  ..|:    ||..|.|.:...|:.|
  Fly   230 ----LTKQQFRAADLQQLQN-----GRKEDLE--KFLFFVNQPAVQKGLGIYLEGLKK 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	76/318 (24%)
		crotonase-like	52..235	CDD:119339	49/202 (24%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	52/223 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810