DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mtpalpha and echdc2

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_997953.1	Gene:	echdc2 / 338247	ZFINID:	ZDB-GENE-030219-147	Length:	301	Species:	Danio rerio

Alignment Length:	215	Identity:	71/215 - (33%)
Similarity:	108/215 - (50%)	Gaps:	7/215 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQ 122
            ||::.:.:....|: ||||.....:...::..|:.:.||...|..|..||.|.||||  :.|..|
Zfish    49 NGIVEVLMCRERAR-NSLGHVFVGQMRDLVSSLQHDSAVRVLVFRSLIPGVFCAGAD--LKERAQ 110

  Fly   123 TAE-EATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVM 186
            .:. ||.|..||.:.:.:.:.....|.:||:.|..|||||||||||..|.|...:  ::||.|..
Zfish   111 MSNAEAELFVHGLRSLMNDIAALPMPTIAAVDGFALGGGLELALACDLRTAAHCA--QMGLIETT 173

  Fly   187 LGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYL 251
            .|||||.||:.|||:......|.::..||::|..::|..||:|:..| |.......|.:..:...
Zfish   174 RGLLPGAGGSQRLPRTVGFAVAKELIFTGRRVGGEQAVNLGLVNRSV-PQNQTGDAAHREALSLA 237

  Fly   252 EKTAVQVANDLASGKLRVNR 271
            .:...|....:...|:.:||
Zfish   238 REILPQAPIAVRMAKVAMNR 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	71/215 (33%)
		crotonase-like	52..235	CDD:119339	65/177 (37%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
echdc2	NP_997953.1	crotonase-like	47..301	CDD:304874	71/215 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810