DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and eci1

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001292513.1	Gene:	eci1 / 334101	ZFINID:	ZDB-GENE-030131-6033	Length:	301	Species:	Danio rerio

Alignment Length:	310	Identity:	89/310 - (28%)
Similarity:	130/310 - (41%)	Gaps:	75/310 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RRLMSTNPAPVANKHLHTKV----VNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVN 97
            |.|:|.|....::|   .||    .|||.|::..||  .||||..:...||...::.||.:.:..
Zfish    32 RYLVSKNDYSTSSK---IKVDLDSSNGVAVLQFQSP--PVNSLSLDFLTEFAINLEKLELDRSCR 91

  Fly    98 SAVLISGKPGCFVAGADIGMLEACQTAEEATLISHGA------QVMFDRMERSKKPIVAAISGVC 156
            ..::.|.:|..|.||.||  ||..|.:.|     |.|      |..:.::..|.|..:|||:|..
Zfish    92 GVIITSAQPKVFSAGLDI--LEMYQKSPE-----HCAEFWKAVQEAWLKLYGSSKVTIAAINGNS 149

  Fly   157 LGGGLELALACHYRIATKDSKTKLGLPEVMLGLLP------------GGGGT---VRLPKLTSVP 206
            ..||..||:.|.|||...:.:..:||.|..||::.            |...|   ::|..|.:.|
Zfish   150 PAGGCLLAMCCDYRIMADNPRYSIGLNETQLGIVAPFWFKDTMLNVVGHRETEKGLQLGLLYNTP 214

  Fly   207 TALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYL--EKTAVQVANDL----ASG 265
            .||               ::|:||.|| |....|..|.:...::|  ...|.|::..:    ...
Zfish   215 NAL---------------KIGLVDELV-PEDKVLSTAAETMTKWLAIPDHARQISKSMMRKPTVD 263

  Fly   266 KLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPLK 315
            ||..|||..           .|:||.   |.|  |..::.|.|:|.|.||
Zfish   264 KLLANREAD-----------TTNFVS---FIT--KDSIQKSLGMYMAMLK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	88/309 (28%)
		crotonase-like	52..235	CDD:119339	61/207 (29%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
eci1	NP_001292513.1	crotonase-like	53..297	CDD:304874	80/284 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810