DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and Eci1

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_059002.2	Gene:	Eci1 / 29740	RGDID:	61892	Length:	289	Species:	Rattus norvegicus

Alignment Length:	188	Identity:	54/188 - (28%)
Similarity:	84/188 - (44%)	Gaps:	29/188 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 GVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQT 123
            |:.|:|..:|  .||||..|...||...::.||.:.::...:|.|.:||.|.||.|:..:.....
  Rat    43 GIAVMKFKNP--PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGLDLMEMYGRNP 105

  Fly   124 AEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLG 188
            |..|.... ..|.::.|:..|...:::||:|....||..:||.|.|||...:.|..:||.|.:||
  Rat   106 AHYAEYWK-AVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRIMADNPKYTIGLNESLLG 169

  Fly   189 LLP------------GGGGTVRLPKL-TSVPTALDMELTGKQVRADRAKRLGIVDLLV 233
            ::.            |.....|..:| |..|.|             .|.::|:||.:|
  Rat   170 IVAPFWLKDNYVNTIGHRAAERALQLGTLFPPA-------------EALKVGLVDEVV 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	54/188 (29%)
		crotonase-like	52..235	CDD:119339	54/188 (29%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
Eci1	NP_059002.2	ECH_1	39..285	CDD:278790	54/188 (29%)
Eci1	NP_059002.2	Substrate binding. /evidence=ECO:0000250\|UniProtKB:P42126	93..97		2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810