DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mtpalpha and CDYL2

DIOPT Version :9

Sequence 1:NP_609299.1 Gene:Mtpalpha / 34276 FlyBaseID:FBgn0028479 Length:783 Species:Drosophila melanogaster
Sequence 2:XP_011521168.1 Gene:CDYL2 / 124359 HGNCID:23030 Length:540 Species:Homo sapiens


Alignment Length:261 Identity:63/261 - (24%)
Similarity:104/261 - (39%) Gaps:37/261 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 GVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGAD----IGMLE 119
            |...|.:.|..:..|:|..|:..|..|.:.:..|:.  :..:|:|.....|.:|.|    ||.|.
Human   293 GFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDD--SKLLLLSAVGSVFCSGLDYSYLIGRLS 355

  Fly   120 ACQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPE 184
            : ...:|:|.|:...:.......:.|||||.||:|..||.|..:...|.  |.....|.....|.
Human   356 S-DRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCD--IVWASEKAWFQTPY 417

  Fly   185 VMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIE 249
            ..:.|.|.|..:...|::..|..|.:|...|:::.|..|...|:|..:..|            ..
Human   418 ATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWP------------TT 470

  Fly   250 YLEKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVL------KASNG 308
            :.::..::| .::||....|..|...||         ..|:|:.:.|...|:.|      .:|.|
Human   471 FSQEVMLRV-KEMASCSAVVLEESKCLV---------RSFLKSVLEDVNEKECLMLKQLWSSSKG 525

  Fly   309 L 309
            |
Human   526 L 526

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MtpalphaNP_609299.1 fa_ox_alpha_mit 38..775 CDD:131494 63/261 (24%)
crotonase-like 52..235 CDD:119339 47/179 (26%)
3HCDH_N 375..553 CDD:280833
3HCDH 556..651 CDD:279114
3HCDH 689..768 CDD:279114
CDYL2XP_011521168.1 CHROMO 40..89 CDD:214605
crotonase-like 286..482 CDD:119339 49/206 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1024
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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