DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtpalpha and Auh

DIOPT Version :9

Sequence 1:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_057918.2	Gene:	Auh / 11992	MGIID:	1338011	Length:	314	Species:	Mus musculus

Alignment Length:	330	Identity:	80/330 - (24%)
Similarity:	138/330 - (41%)	Gaps:	73/330 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KHLHTKVVNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGAD 114
            :||..: ..|::|:.|:....| |:|...:.....:.:..|:::..|.:.::.|..||.|.||||
Mouse    55 RHLEEE-NRGIVVLGINRAYGK-NALSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGAD 117

  Fly   115 IGMLEACQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTK 179
            :.......::|....:|....|:.| :.....|.:|||.|:.|||||||||||..|:|.  |..|
Mouse   118 LKERAKMHSSEVGPFVSKIRSVIND-IANLPVPTIAAIDGLALGGGLELALACDIRVAA--SSAK 179

  Fly   180 LGLPEVMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAE 244
            :||.|..|.::||||||.|||:...:..|.::..:.:.:....||.:|::..::          |
Mouse   180 MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGQEAKAVGLISHVL----------E 234

  Fly   245 QNTIEYLEKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGL 309
            ||                                      .:.|....|..|.||:.:.:.
Mouse   235 QN--------------------------------------QEGDAAYRKALDLAREFLPQG---- 257

  Fly   310 YPAPLKILDV-IRAGVDKGTDAGYEAERKGFGELSATPES-KGLIALFRGQTECKKNRFGKPERP 372
             |..:::..: |..|::.....|...|...:.:..:|.:. :||:|.             |.:||
Mouse   258 -PVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAF-------------KEKRP 308

  Fly   373 VKTVG 377
            .:..|
Mouse   309 PRYKG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	80/330 (24%)
		crotonase-like	52..235	CDD:119339	58/182 (32%)
		3HCDH_N	375..553	CDD:280833	1/3 (33%)
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
Auh	NP_057918.2	crotonase-like	61..314	CDD:304874	78/323 (24%)
Auh	NP_057918.2	RNA-binding. /evidence=ECO:0000250\|UniProtKB:Q13825	80..94		0/13 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900