DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brwl and jigr1

DIOPT Version :9

Sequence 1:	NP_609298.1	Gene:	brwl / 34275	FlyBaseID:	FBgn0032130	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001097920.1	Gene:	jigr1 / 43093	FlyBaseID:	FBgn0039350	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	52/297 - (17%)
Similarity:	96/297 - (32%)	Gaps:	79/297 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GSGTAGASIGSTNRVMQADEDFNIRFVNLVRTHKCLYDKKVPEYRNRDNQEKAWVLISKETRESV 100
            |.|...|:...|.       :|::..:...|:|..|||:....::::......|..|:.:.....
  Fly    15 GRGRPRATYAQTG-------EFDLGLIREYRSHPVLYDRSNKRFKDKLYVAHIWEQIAHKLGYDA 72

  Fly   101 IHCKERWRNLRACLSRY----IKQQSGSEPQHKPYYLTEHMAFLLPFLKSSRNSLEGNNSLATLY 161
            ...:||...||   :||    .:.::|...|...:.|.|.:.||
  Fly    73 TSIRERMTTLR---NRYNIEKRRVENGLSTQSSQWPLFESLQFL--------------------- 113

  Fly   162 QMSQQHLQHQPFLLHPALHATEEHKYCANTSINNNNNNNDVHNGESMEVLEMKYSISEKDDEETI 226
               ..|::.:....:.::...:|..|    .:::..::::.|.....:.||        ||.|..
  Fly   114 ---GDHIRPRRSFKNMSVKEEDEETY----EVDDCRSDSNGHMNSIKDELE--------DDSEIF 163

  Fly   227 DAFDP-AVTNTLG--MNRT-----SSTPTRSSALQGGGGNSPARSDTASADSMKNFIPDVQLAET 283
            |.... .||..||  :|.:     |...|......|.|.|..|.|......:...:|....:..
  Fly   164 DCEQALPVTTVLGIPLNNSDEANKSQRSTNGEMPNGKGYNHFAESYHRRHQNQPEYIISSPIVN- 227

  Fly   284 GSQLIYSDGGHGTPPPLHYHPHSHPHPLTLSMDHHPA 320
                           |:..:.....|     :|.||:
  Fly   228 ---------------PMRSNKRGSQH-----LDDHPS 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brwl	NP_609298.1	MADF	60..145	CDD:214738	19/88 (22%)
brwl	NP_609298.1	BESS	356..389	CDD:281011
jigr1	NP_001097920.1	MADF	33..118	CDD:214738	20/111 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930