DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment brwl and stwl

DIOPT Version :9

Sequence 1:	NP_609298.1	Gene:	brwl / 34275	FlyBaseID:	FBgn0032130	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001261839.1	Gene:	stwl / 39581	FlyBaseID:	FBgn0003459	Length:	1037	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	106/496 - (21%)
Similarity:	167/496 - (33%)	Gaps:	146/496 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 MQADEDFNIRFVNLVRTHKCLYDKKVPEYRNRDNQEKAWVLISKETRESVIHCKERWRNLRACLS 115
            |.|..:.|:..:..|.....|||:....||.|...|.||.:::.|..|||..||.|||.||...:
  Fly     1 MSAASEVNLMLLRSVEKQTALYDRTDENYRKRLPSENAWDMVASEVGESVEKCKRRWRQLRNDYT 65

  Fly   116 RYI-----KQQSGSEPQHKPYYLTEHMAFLLPFLK-------------SSRNSLEGNNSLATLYQ 162
            |:.     ::::|.  :...|.|.:.:.||...|.             ||....:.|.....:..
  Fly    66 RWCNADANRRRNGQ--RRLAYPLADELRFLDRHLNIADDMAADDDRSVSSDKDRDNNRDSEGVDH 128

  Fly   163 MSQQHLQHQPF----LLHPALHATEEHKYCANTSINNNNNN----------------NDVHNGES 207
            .:|..|:.:..    |:.....|::..|..::.....|..|                ||:...:.
  Fly   129 HAQASLKERASSTSKLVKEVKLASQVRKEKSSQDKRENWENPGDKQRSRKKSAEEKLNDLEESDE 193

  Fly   208 ME-VLEM-KYSISEKDDEETIDA----------FDPAVTN---------TLGMNRTSST------ 245
            .| |.|: .:..|:.:|:|.:|.          ||...:|         :|..|.|.||
  Fly   194 PEKVPELDSFLQSDNEDDECMDEEHLEDLEGFDFDLEQSNQEKELTPEKSLEKNNTDSTVSQPEF 258

  Fly   246 ---PTRSSALQGGGGNSPARS---------------DTASADSMKNFIPDVQLAETGSQLIYSDG 292
               .||...|...|..:...|               :||..||...:..|.:...|||.
  Fly   259 FVKQTRDPRLLIIGRKNSTSSFAESKASKSISGDPLETAMEDSGDEYGRDGEKRVTGSD------ 317

  Fly   293 GHGTPPPLHYHPHSHPHPLTLSMDHHPASYEPGSTKRIKTECEATSTMTNAGSIYGGLSSSEVAD 357
               |..|......:....::.:........:||..:|: |..:...:|:.| :::...||:....
  Fly   318 ---TTSPTRRPRRAARASISFAGIRDLPIQKPGQAQRM-TRLQRRKSMSLA-AVHSVRSSTSPVK 377

  Fly   358 MEFFRSILPDLATLTPQQR----RKFKIGILELI-----DDVVTRYPAQDHSNGGGVSGVVN--- 410
            |             ||..|    .|...|.:::.     ||:..| ||..       |||||
  Fly   378 M-------------TPVPRSQPINKPPSGPVQITKISHRDDIFPR-PAVP-------SGVVNINQ 421

  Fly   411 -----------------GSGGSSNGGSVKHQRRSSGRDWRK 434
                             ....::..||...||||.||..:|
  Fly   422 NQLKTQQQQKTLIFPTTDEAIANPQGSGPPQRRSVGRPPKK 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brwl	NP_609298.1	MADF	60..145	CDD:214738	27/89 (30%)
brwl	NP_609298.1	BESS	356..389	CDD:281011	6/41 (15%)
stwl	NP_001261839.1	MADF	11..98	CDD:214738	27/88 (31%)
stwl	NP_001261839.1	BESS	604..637	CDD:281011
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000