DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brwl and CG6683

DIOPT Version :9

Sequence 1:	NP_609298.1	Gene:	brwl / 34275	FlyBaseID:	FBgn0032130	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_648232.1	Gene:	CG6683 / 38970	FlyBaseID:	FBgn0035902	Length:	197	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	45/221 - (20%)
Similarity:	73/221 - (33%)	Gaps:	76/221 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 FNIRFVNLVRTHKCLYDKKV---PEYRNRDNQEKAWVLISKETRESVIHCKERWRNLRACLSRYI 118
            |:.|.:.|||.:..||::::   |...::....:.|..|:.........|..||.:|.|...|.:
  Fly     4 FDTRLIELVRANPKLYERELRNAPYEAHKKRHPEIWSSIATSLNSEASACVSRWNHLVAKQRREL 68

  Fly   119 KQQ----SGSEPQHKPYYLTEHMAFLLPFLKSSRNSLEGNNSLATLYQMSQQHLQHQPFLLHPAL 179
            .::    :||:     :.|..|:.||                         || .|.|.
  Fly    69 AKEKAGGTGSD-----WSLLPHLKFL-------------------------QH-HHHPI------ 96

  Fly   180 HATEEHKYCANTSINNNNNNNDVHNGESMEVLEMKYSISEKDDEETI-DAFD---------PA-V 233
                           |:.|:.|:...      .:|.|....|||:.: :|.|         || .
  Fly    97 ---------------NHRNSGDLSRS------TLKSSDEVNDDEDPLQEAMDEQLAVAGAAPAPP 140

  Fly   234 TNTLGMNRTSSTPTRSSALQGGGGNS 259
            ||.......:....|..||..|.|.:
  Fly   141 TNPAHATPVAQAEKRIEALLEGLGEA 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brwl	NP_609298.1	MADF	60..145	CDD:214738	21/91 (23%)
brwl	NP_609298.1	BESS	356..389	CDD:281011
CG6683	NP_648232.1	MADF	7..94	CDD:214738	23/117 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100