DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brwl and CG13204

DIOPT Version :9

Sequence 1:	NP_609298.1	Gene:	brwl / 34275	FlyBaseID:	FBgn0032130	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_610678.1	Gene:	CG13204 / 36227	FlyBaseID:	FBgn0033627	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	79/343 - (23%)
Similarity:	127/343 - (37%)	Gaps:	92/343 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 FVNLVRTHKCLYDKKVPEYRNRDNQEKAWVLISKETRESVIHCKERWRNLRACLSRYIKQ-QSGS 124
            |:.:|:.:..:|:...|:|:|.:.:.|.|..|:.|...||...|.:|:|||...::|::. :.|:
  Fly    23 FIEIVKKYDVVYNNHNPDYKNVEVKLKVWTQIADEIGLSVEASKRKWKNLRDSYTKYLRSFRVGT 87

  Fly   125 EPQHKPYYL--TEHMAFLLPFLKSSRNSLEGNNSLATLYQMSQQHLQHQPFLLHPALHATEEHKY 187
            :...|..|.  .:||.||.||....|||..||
  Fly    88 KTSKKYQYWAHADHMDFLKPFQGPGRNSANGN--------------------------------- 119

  Fly   188 CANTSINNNNNNNDVHNGESMEVL----------EMKYSISEKD------DEETIDAFDPAVTNT 236
                  ..:|:.:|.......:||          |:|.:|:...      ...|::.:..|:::|
  Fly   120 ------GKSNDEDDTECDFGYQVLAKAASNGGEDELKITIATASAGCSSMGTHTVNTYTTALSST 178

  Fly   237 LGMNRTSS----TP----TRSSALQGGGGNS----PARSDTASADSMKNFIPDVQLAETGSQLIY 289
            .....|||    ||    :..|.|.|.||.|    |...::.|..|....:....:|...|.
  Fly   179 SASGITSSLGATTPPNMISPGSNLGGTGGGSGSVGPQIHNSNSNGSATGSLNCAAVAPLSSM--- 240

  Fly   290 SDGGHGTPPPLHYHPHSHPHPLTLSMDHHPASYEPGSTKRI-KTECEATSTMTNAGSIYGGLSSS 353
                  |||.......:...||.:|    |||....:...: |....|.:::.|  .:..||..|
  Fly   241 ------TPPATSGSNSAVVLPLPIS----PASSVAAAAAAVSKANANALASLAN--HLPMGLGVS 293

  Fly   354 EVADMEFFRSILPDLATL 371
            .:|...|      .||||
  Fly   294 GLAQQMF------PLATL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brwl	NP_609298.1	MADF	60..145	CDD:214738	27/86 (31%)
brwl	NP_609298.1	BESS	356..389	CDD:281011	6/16 (38%)
CG13204	NP_610678.1	MADF	22..108	CDD:214738	25/84 (30%)
CG13204	NP_610678.1	BESS	478..510	CDD:281011
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910