DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment brwl and CG12155

DIOPT Version :9

Sequence 1:	NP_609298.1	Gene:	brwl / 34275	FlyBaseID:	FBgn0032130	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_572403.1	Gene:	CG12155 / 31682	FlyBaseID:	FBgn0029957	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	62/312 - (19%)
Similarity:	108/312 - (34%)	Gaps:	108/312 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 ADEDFNIRFVNLVRTHKCLYDKKV-PEYRNRDNQEKAWVLISKE--TRESVIHCKERWRNLRACL 114
            |..|..:..:||||.:..||:.|: |..|.|.:....|..::::  .:.:|...:.:|:|||...
  Fly    16 APTDDILTLINLVRQNPVLYNYKLQPNQRRRSDVLNGWQEVAQQIGNKYTVQEVRRKWKNLRDTF 80

  Fly   115 SRY-IKQQSGSEPQHKPYYLTEHMAFL----LPFLKSSRNS---------------LEGNNSLAT 159
            .:| ::.....|.:...:...:.:.||    .|.|||.||:               :.|.|| .|
  Fly    81 HQYRLRTPKYIEGRLSKWRYAKELDFLSKVYQPKLKSHRNTQITYETSGVAGAGGGIGGANS-TT 144

  Fly   160 LYQMSQQHLQHQPF--LLHPALHATEEHKYCANTSINNNNNNND-------VHNGESMEVLEMKY 215
            |           |.  :||...|..::     :..:.:::..:|       .|:|.|...|
  Fly   145 L-----------PIGAMLHLKQHVDDD-----DDEVMDDDGQSDHDTATLSSHHGTSQITL---- 189

  Fly   216 SISEKDDEETIDAFDPAVTNTLGMNRTSSTPTRSSALQGGGGNSPARSDTASADSMKNFIPDVQL 280
             :|::.:...:.|::..|::                            ||.|..
  Fly   190 -VSDEAETFILTAYEEGVSD----------------------------DTVSQH----------- 214

  Fly   281 AETGSQLIYSDGGHGTPPPLHYH-PHSHPHPLTLSMDHHPASYEPGSTKRIK 331
                    :....||.....|:| ||.|.|      .||..|...||...|:
  Fly   215 --------HHHHHHGHHQQEHHHQPHHHHH------HHHHQSQHDGSISSIE 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brwl	NP_609298.1	MADF	60..145	CDD:214738	21/92 (23%)
brwl	NP_609298.1	BESS	356..389	CDD:281011
CG12155	NP_572403.1	MADF	24..112	CDD:214738	20/87 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000