Protein Alignment Oatp30B and Slco1a5

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_110465.1
• Gene: Slco1a5 / 80900
• RGDID: 70985
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 711
• Identity: 222/711 - (31%)
• Similarity: 355/711 - (49%)
• Gaps: 135/711 - (18%)

  Fly   163 IQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFV 227
            ::.|::||:|::.|: ...:.::||..|:|:::|.||::|:||:|..|.|..|:||||::.:|||
  Rat    13 VRCFSKIKMFLLALT-WAYVSKSLSGIYMNTMLTQIERQFDIPTSIVGFINGSFEIGNLLLIIFV 76

  Fly   228 SYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGR 292
            ||.|::.|.|:.||:|.||||:|..:..:|||.                             :||
  Rat    77 SYFGTKLHRPIMIGVGCVIMGLGCFLMSLPHFL-----------------------------MGR 112

  Fly   293 LSSGLSNQPLAPHTLREDNCLEGKASTTGP--------------VLLFVL-AQLLLGCGGSPLFT 342
            .....:..|.:..:.....|:|.::.|..|              :.::|| ..::.|.|.:|:..
  Rat   113 YEYETTISPTSNLSSNSFLCMENRSQTLKPTQDPAECIKEMKSLMWIYVLVGNIIRGIGETPIMP 177

  Fly   343 LGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPGDRRWV 405
            ||.:|::|..::|:|.:|||.:.:...|||:||.|||::..|.::|  |:::..::|||.|.|||
  Rat   178 LGISYIEDFAKSENSPLYIGILETGKVFGPIVGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWV 242

  Fly   406 GMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLE 470
            |.||.|||:|..:.::.::|||.|||.|.:|..:                     |::....
  Rat   243 GAWWIGFLICAGVNILSSIPFFFFPKTLPKEGLQ---------------------DDVDGTN--- 283

  Fly   471 IVAVTSKEDQSQAPPKVDT-GYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPK 534
                ..||::.:...|.:. |..||.....:|   |..||:|::..|.:.:::........||||
  Rat   284 ----NDKEEKHREKAKEENRGITKDFLPFMKS---LSCNPIYMLLILTSVLQINAFINMFTFLPK 341

  Fly   535 YLETQFSLGKSQANI--FTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAM 597
            |||.|:  |||.|.:  ..|...:|..|||..|.|.|:|:|::..|.|.......::.....|.:
  Rat   342 YLEQQY--GKSTAEVVLLIGVYNLPPICIGYLLIGFIMKKFKITVKKAAYMAFCLSLFEYLLYFL 404

  Fly   598 LFFLGCDNLKMAGTTI-------PYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNN 655
            .|.:.|||..:||.|.       |.|..||            :.|.||.||.|.|:..:||||:|
  Rat   405 HFMITCDNFPVAGLTASYEGVHHPLYVENK------------VLADCNRGCSCSTNSWDPVCGDN 457

  Fly   656 GLTYFSPCHAGCTAFSST-SNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVA 719
            ||.|.|.|.|||.....| :|..:.||:|:|::.:||                      .|:.:.
  Rat   458 GLAYMSACLAGCKKSVGTGTNMVFQNCSCIRSSGNSS----------------------AVLGLC 500

  Fly   720 TAGP-CATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIP 783
            ..|| ||   ..:..|||:....:|:.:.|.:|..|::||.:..||:|..:|:.....|:|..||
  Rat   501 KKGPECA---NKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKPEEKSLGIGLHAFCTRVFAGIP 562

  Fly   784 APILFGNLIDSTCILWKS-SCGEKGGRCLIYDIEKFRYKYVGLCASVK----LIALVIFMV 839
            |||.||.|||.||:.|.: .|||.|. |.:|:|..||..|:.|.|:::    |.||.|.::
  Rat   563 APIYFGALIDRTCLHWGTLKCGEPGA-CRMYNINNFRRIYLVLPAALRGSSYLPALFILIL 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	183/616 (30%)
		UhpC	<730..795	CDD:441872	25/64 (39%)
Slco1a5	NP_110465.1	oat	1..625	CDD:273279	222/711 (31%)