Protein Alignment Oatp30B and slco1f4

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_001074135.2
• Gene: slco1f4 / 791184
• ZFINID: ZDB-GENE-070112-2172
• Length: 644
• Species: Danio rerio
• Alignment Length: 705
• Identity: 224/705 - (31%)
• Similarity: 343/705 - (48%)
• Gaps: 114/705 - (16%)

  Fly   169 IKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSR 233
            :|||:..|: .....::::..|..|.||.||||||||||..|.|..|:|:||::.:..|||:|::
Zfish    26 LKIFICALA-FSYFSKSMTGSYTKSTITQIEKRFEIPSSTVGFIDGSFEMGNMLVITLVSYIGAK 89

  Fly   234 RHIPVWIGIGAVIMGIGSLVFMVPHF-TGEPNPGIAIV------NKTSDNICKSALVRDQDMDLG 291
            .|.|..||.|.::||||:|:...||| .|....|.|..      |.|..:.|.|    |....|.
Zfish    90 FHRPKIIGAGVLLMGIGTLLMASPHFLMGRYKYGTAATHTNDAGNFTVISTCSS----DSQETLQ 150

  Fly   292 RLSSGLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTES 356
            :..||               |.:.:|.::...::.||...:.|.|.:.:..||.:::||:.|.|:
Zfish   151 QPFSG---------------CQKEEAESSPFWVIVVLGNTMRGIGEASIVPLGMSFIDDYARPEN 200

  Fly   357 SSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPGDRRWVGMWWGGFLLCGVIL 419
            |:.|||.:.::...||:.|::||:...:.::|  .:...:::|||.|.||||.||.|:::.|::.
Zfish   201 SAFYIGCLNTLKGIGPIFGYMLGSLCANLYVDFGLVDQESVTITPQDSRWVGAWWLGYVVSGLLT 265

  Fly   420 LVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAP 484
            |:.|.||:..||                 |||.||               :|..:.:...|.:..
Zfish   266 LLAAFPFWFLPK-----------------VLPENS---------------QISLLDNTPQQHKTT 298

  Fly   485 PKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVV---FLPKYLETQFSLGKSQ 546
            |.:.    :.:||...:..||:.|.:||   |.....::..:.|.:   :.|||||.||....|:
Zfish   299 PSLT----EIVKDFAPTFKRLLTNKIYI---LYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASK 356

  Fly   547 ANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGT 611
            ||...|..::|...:|:||.|.::|||:.....:.:..|:|.|..:......|.|.|:||.:||.
Zfish   357 ANFLIGVTSIPAVALGVFLSGLMMKRFKWGLLASARVNLLTIVATVFLAVPFFALSCENLDIAGV 421

  Fly   612 TIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFSSTS-N 675
            |:||     .|||..|....::..:||..|.|...:.:||||.||:||.|||||||.:..... |
Zfish   422 TVPY-----QGSTEVQGVTSDVLPSCNADCGCPDLQWDPVCGENGVTYISPCHAGCNSTQGAGRN 481

  Fly   676 TNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPCA--TPC-RTIYPFLIL 737
            ..:.:|.|:               |:..||...:        .|..|.|:  ..| |.||.:|.|
Zfish   482 MTFHDCRCI---------------QSWGLSVGNS--------SAVLGQCSRDPKCNRMIYIYLGL 523

  Fly   738 LFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILW--K 800
            .....||.....:|...:.||.|..|.:|.::||..:..|:.|.|||||.||.||||||:.|  .
Zfish   524 QSLAFFLCGLGIIPFFTMSLRIVDPELKSLSVGMLLLAVRVLGGIPAPIYFGALIDSTCLKWGQN 588

  Fly   801 SSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVR---RRKQLEK 852
            .|||.  |.|.|||||.||:.:.||...::::|..:.    |:..   :||..|:
Zfish   589 KSCGR--GACRIYDIETFRFLFQGLTMCLRVLACSLL----WIATIEIKRKNTEQ 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	182/603 (30%)
		UhpC	<730..795	CDD:441872	26/64 (41%)
slco1f4	NP_001074135.2	MFS	26..544	CDD:475125	182/604 (30%)