Protein Alignment Oatp30B and Slco6d1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_011246380.1
• Gene: Slco6d1 / 70866
• MGIID: 1918116
• Length: 729
• Species: Mus musculus
• Alignment Length: 754
• Identity: 199/754 - (26%)
• Similarity: 329/754 - (43%)
• Gaps: 130/754 - (17%)

  Fly   114 PSAV---ADSVTVKCHSRQASAGKCPADPEEDFDEEQFRSGDCGILNCRPYG--------IQRFA 167
            |:||   ||:..:|...|:..      ||.|:                 |||        :|||.
Mouse    40 PTAVKKFADTPDMKKSDRKYK------DPSEE-----------------PYGLGSLVFPCLQRFN 81

  Fly   168 RIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGS 232
            .:|.|:. ||.|.::..::....::..|.....:.........|:.:|......:..:||::.|.
Mouse    82 NVKSFLT-LSFLAVVAHSMIFALVDQSIKLYVAQLSPSRIEEYLMDTSDNFVAFLFSMFVAHFGG 145

  Fly   233 RRHIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLSSGL 297
            |.:...|:..|..:.||.::||.||....|              |.|.::|:::..:.|:|.. :
Mouse   146 RGNRANWVAAGCFLTGIAAIVFAVPFLNFE--------------IIKLSVVKEELCEEGKLPK-V 195

  Fly   298 SNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIG 362
            ....:.||   :..|          :.:|:..|.|.|..|.||:.|.|:::.|||.|.||.:||.
Mouse   196 CEPTVLPH---KSIC----------IFIFIFGQCLHGIAGLPLYILATSFIFDHVPTNSSGLYIA 247

  Fly   363 FMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGM----WWGGFLLCGVILLVVA 423
            .:.:....|..:||:.|  :|:|.|   |:..:....|.|:.:.:    ||..|:...|......
Mouse   248 LVDAALGVGYCLGFIGG--MLNFKM---SAQEVMQAVGHRQRIRILQRGWWRTFIFVAVFAFCTT 307

  Fly   424 VPFFSFPKVL--AREKKKIRKSSVVQP----------VLPNNSRATVATDEMGKVKKLEIVAVTS 476
            :|...||..|  ||:   ||.....:|          .:.||.::.:....:.....|.|::.|.
Mouse   308 LPLLGFPSSLPGARQ---IRLEKSQEPPTFDRRLKNKEIKNNLKSVLHATWIYHRGHLTILSQTC 369

  Fly   477 KEDQ-----SQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYL 536
            ....     |.....:|    .|::.:.|.   |::||:.:...:....|........||||:||
Mouse   370 STSLGGICCSTTGKAID----GDLQKLTQC---LIRNPLVLSQVVCKFTEFTTFKSSAVFLPQYL 427

  Fly   537 ETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFL 601
            :|:|.:..|.|::.||...:||:..|.|.||.|:.|.|:..|..::|:::.:.:.:..:.:.||:
Mouse   428 QTRFLIRPSSASMLTGVFILPGSIFGHFFGGFIVHRMQMNNKNKLKFLVVASFVSIVLFLLTFFV 492

  Fly   602 GCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAG 666
            .|:..|.||....|......|         ||||.||..|.|.|||..||||.:...|||||.||
Mouse   493 ECEISKFAGINDDYDRLGIIG---------NLTAPCNVPCGCTTSEYNPVCGRDETQYFSPCFAG 548

  Fly   667 CTAFSS-TSNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPCATPCRT 730
            |.|... .....|.||:|::..::::      .::.|.:.             |.:|.|.|.|.|
Mouse   549 CKATKKLRKEKTYYNCSCIKEGLTTA------DNEGQYID-------------AVSGTCNTRCLT 594

  Fly   731 IYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDST 795
            :..|....|..|||.:...:|..:||::||.....|.:||:...::|..|.:||||||....|.|
Mouse   595 LPLFFAFYFTATFLSSFCSIPSALIVIQSVPTSWNSMSLGLMSTVWRFTGSVPAPILFAATSDFT 659

  Fly   796 CILWK-SSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIA 833
            |..|. :.|||| .||.||:.|...|.:..:..::::::
Mouse   660 CQFWGINECGEK-VRCWIYNTENLVYTFKTVWINMQILS 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	156/609 (26%)
		UhpC	<730..795	CDD:441872	23/64 (36%)
Slco6d1	XP_011246380.1	MFS	83..622	CDD:475125	156/610 (26%)