Protein Alignment Oatp30B and slco1b3

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_031753845.1
• Gene: slco1b3 / 613085
• XenbaseID: XB-GENE-5943217
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 708
• Identity: 214/708 - (30%)
• Similarity: 351/708 - (49%)
• Gaps: 111/708 - (15%)

  Fly   160 PYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITV 224
            |..:...:.:|:|:|.| ......:|.|..|:.|.||.||:||:|.||..|:|..|:||||::.:
 Frog    31 PQKVSCCSNLKMFLVAL-CFSYFAKAFSGSYMKSSITQIERRFDISSSTVGMIDGSFEIGNLMVI 94

  Fly   225 IFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHF---------TGEPNPGIAIVNKTSDNICKS 280
            ..|||.|::.|.|..|..|.::|.:||.:..:|||         .|.|         ||.|  .:
 Frog    95 AIVSYFGAQFHRPRIIAAGCILMSLGSFLTAMPHFFMGLYKYETVGGP---------TSLN--SN 148

  Fly   281 ALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGT 345
            |.:        .:|..|:|:.|. .|.:.| |:....|.....||  :..:|.|.|.:|:..||.
 Frog   149 ATI--------NVSPCLANRSLV-DTPKPD-CVTENGSHMWVFLL--VGNILRGIGETPIAPLGI 201

  Fly   346 TYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPGDRRWVGMW 408
            :|:||..|.|::.::|..::::..|||:.||:||::|...::|  .:.:.||:|||.|.||||.|
 Frog   202 SYLDDFSRPENTPLHIACLHTVAMFGPMTGFMLGSFLARLYVDIGFVDTDTITITPQDTRWVGAW 266

  Fly   409 WGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVA 473
            |.||||.|.:.|:.|:|||..|:.|..|:::.:|....|            .:|.|
 Frog   267 WIGFLLSGAVNLMSAIPFFFLPESLKEEQREGQKPQTKQ------------GEEKG--------- 310

  Fly   474 VTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVS---GFVVFLPKY 535
                ..|.:.|         .::....::..|..|.::::.   .|:.|:..:   ||:.:.|||
 Frog   311 ----HKQKEKP---------TLRGFFAALKTLCFNRLFVML---MCLTLLQTNSFLGFITYKPKY 359

  Fly   536 LETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFF 600
            :|.|:....|:||..||...:|.|.:|:||||.|:||::....||.:....|:::........||
 Frog   360 MEQQYGQSISKANFVTGVSTLPAAALGMFLGGLIMKRYKFGLLGASKMAYGTSLLAFLLSLSAFF 424

  Fly   601 LGCDNLKMAGTTIPY---YTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSP 662
            :||:|..:||.|:.|   ..:|.....:..|        ||..|.|.:.:.:||||.||:||.|.
 Frog   425 IGCENNNVAGITVTYDRVKVNNFQDRIIYSP--------CNSDCHCSSKQWDPVCGENGVTYVSA 481

  Fly   663 CHAGCTAFSSTS-NTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPCAT 726
            |.|||.|.:.:. .|.|.||:|:...:|:::     .|.|...|.                |...
 Frog   482 CLAGCKASTGSGLGTVYHNCSCIDTALSTAV-----NSSAHLGSC----------------PRGP 525

  Fly   727 PCRTIYPFLILL-FFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGN 790
            .|..::.|.::. ...||:.|.......:::|.||:.|.:|.|:|:..::.|....|||||.||.
 Frog   526 DCSRMFMFYVVTQAINTFIFALGASSAYVLLLWSVNPEMKSLAVGVYMLLIRTLAGIPAPIYFGA 590

  Fly   791 LIDSTCILWKSS-CGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRR 847
            :||.:|:.|.:. ||.:|. |.:||.:.||.:::||.|.::..:.::|.:...:|:||
 Frog   591 IIDKSCLKWGTRLCGGRGA-CRLYDADSFRRRFLGLTAGIRAPSYILFFIFIVMVKRR 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	203/666 (30%)
		MFS	174..>433	CDD:119392	96/269 (36%)
		MFS	512..>600	CDD:304372	27/90 (30%)
		KAZAL_SLC21	633..684	CDD:238650	22/51 (43%)
slco1b3	XP_031753845.1	MFS_SLCO1B_OATP1B	40..558	CDD:341015	179/607 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000