Protein Alignment Oatp30B and slco5a1a

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_001340277.1
• Gene: slco5a1a / 570033
• ZFINID: ZDB-GENE-090316-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 627
• Identity: 216/627 - (34%)
• Similarity: 319/627 - (50%)
• Gaps: 110/627 - (17%)

  Fly   361 IGFMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVP 425
            :..||.|||.||..|:|||..|:.|::|  ..|.::|..||.|:||.||.|||||.|.:|:|..|
Zfish     9 LAIMYVMGALGPAAGYLLGGILIGFYVD--PGTVVNIDQGDPRFVGNWWSGFLLCAVAMLLVIFP 71

  Fly   426 FFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTG 490
            .|||||.|...:||.::.      :...:....:.|||.|.|.   .||:|           ..|
Zfish    72 MFSFPKKLPPRQKKSKRG------VKKGAGDVSSDDEMMKEKS---QAVSS-----------SMG 116

  Fly   491 YGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIA 555
            :||:|||:|::.:|::.|..::...|....|..||:.|:.|:||::|:||.:..|.|:|:||.|.
Zfish   117 FGKNIKDLPKAAVRILSNVTFLFVSLSYTAECAIVTAFITFIPKFIESQFGVPASSASIYTGLII 181

  Fly   556 VPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSNK 620
            ||.|.:||||||.|:|:.:|..:.|.:..:|.:.:.|.|::.||.:||:::.:.|..|||.|
Zfish   182 VPSAGVGIFLGGYIIKKLKLGAREAAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT--- 243

  Fly   621 HGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFSSTSN--TNYTNCAC 683
             |.||....: |||.:||..|.|...|..||||::|:|||:||.|||:..::.::  .||::|||
Zfish   244 -GPTLTLSHR-NLTGSCNVNCGCKIHEYAPVCGSDGITYFNPCLAGCSNIANHTSGIRNYSDCAC 306

  Fly   684 VRANISSSIYRGAGGSQAQAL-----SANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTF 743
            |:   |..:...:||:....|     ..|||       ..|.||.|...|.|:..|||.||.:|.
Zfish   307 VQ---SRQVITPSGGNHELQLVIVKTYLNEN-------GFALAGKCERTCGTLITFLIFLFIVTL 361

  Fly   744 LVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGG 808
            :.|..|..::::.||||.||:|.||||||||:.|...|||.||.||.:||:||:||:..||..|.
Zfish   362 ITACAQPSVIIVTLRSVDEEDRPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGFHGS 426

  Fly   809 RCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQLEKMKPLNASDPIIGSIISLDKLF 873
             |..||:...|:.|.||.||:|.:..:...:.|:.::||
Zfish   427 -CWEYDVTSLRFVYFGLAASLKFLGFLFIFLTWYSLKRR-------------------------- 464

  Fly   874 EEKLSGAEPSTAFVGGGGELIIPTDILRHSRNDSRTMHMDYCYDKCGRVVTPANTCNQPQTKSKK 938
            ||:                        .|:.....|:.   ..|....::..|.       ..|.
Zfish   465 EEQ------------------------THTHTHQHTLS---TLDTVSHLICHAG-------GHKG 495

  Fly   939 HFRSASCDVKMIKSFARDHSSSSGP---ADAAGQDAVGASTK 977
            |.|:.||.|.:.:.|  :||.::||   |.:.|....|...|
Zfish   496 HARTRSCPVFLPRPF--EHSHNAGPPGHALSRGNSCPGNGLK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	185/463 (40%)
		MFS	174..>433	CDD:119392	37/71 (52%)
		MFS	512..>600	CDD:304372	34/87 (39%)
		KAZAL_SLC21	633..684	CDD:238650	24/52 (46%)
slco5a1a	NP_001340277.1	OATP	<9..435	CDD:308646	185/463 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	457	1.000	Domainoid score	I476
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	483	1.000	Inparanoid score	I1411
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123298at33208
OrthoFinder	1	1.000	-	-		FOG0007263
OrthoInspector	1	1.000	-	-		oto40128
orthoMCL	1	0.900	-	-		OOG6_101062
Panther	1	1.100	-	-	LDO	PTHR11388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.870