Protein Alignment Oatp30B and slco3a1a

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_001038653.1
• Gene: slco3a1a / 569735
• ZFINID: ZDB-GENE-030131-8662
• Length: 701
• Species: Danio rerio
• Alignment Length: 772
• Identity: 270/772 - (34%)
• Similarity: 411/772 - (53%)
• Gaps: 101/772 - (13%)

  Fly   129 QASAGKCPADPEEDFDEEQFRSGDCGILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINS 193
            |....:...||:.|   :..:...|            |:.||||:| ....:|:.|.....|:.|
Zfish     2 QVKKQRSSEDPQRD---DIKKKPSC------------FSNIKIFLV-AECALMLAQGTVGAYLVS 50

  Fly   194 VITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPH 258
            |:||:|:||.:.|:..|:||||:||||:..::||||.|::.|.|..||.|.::|.:|:|:..:|.
Zfish    51 VLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGAKAHRPRLIGCGGIVMALGALLSALPE 115

  Fly   259 FTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGPV 323
            |       :|...|.:|...|     ||..|            :..:|.:.|.....:|:|....
Zfish   116 F-------LASQYKITDTWSK-----DQGRD------------VCSNTSKADEPCGNRANTNMMY 156

  Fly   324 LLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD 388
            ||.:.||:|||.|.:|:..||.:|:|||||.:.||:|||.::|...|||..||:||:...:|::|
Zfish   157 LLLIGAQVLLGIGATPVQPLGVSYIDDHVRKKDSSLYIGILFSTLVFGPACGFILGSVCTNFYVD 221

  Fly   389 SL--SSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVL-AREKKKIRKSSVVQPVL 450
            :|  .:|.::|||.|.||:|.||||||:||.:|...|:..|.||:.| ::|.:.:.:|.  |.:|
Zfish   222 ALFIDTTQLNITPDDPRWIGAWWGGFLICGALLFFSALFMFGFPQSLPSKEMEGVPESE--QAML 284

  Fly   451 PNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTC 515
            |    |:::.| ..|.|....|.      |:..|........:.::.||:....|:.|||:....
Zfish   285 P----ASLSQD-FEKSKPSNGVV------QNYQPNSNSLSCCQQLRVIPKVTKHLLSNPVFTCIV 338

  Fly   516 LGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGA 580
            |.||||:.:|:||..||.||||.||:|..|.||...|..|:|.||:||||||.::|:..|...||
Zfish   339 LAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLNLSALGA 403

  Fly   581 VQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSN-KHGSTLEQPFQVNLTAACNFGCECL 644
            ::..::.|:|..|||....|||||...:||.|:.|.... :.|.|.|.|        |...|.|.
Zfish   404 IRMAMLVNLISTACYVSFLFLGCDTGPVAGVTVAYGNETLQVGQTPEAP--------CMSHCNCY 460

  Fly   645 TSEVEPVCGNNGLTYFSPCHAGCTAFSSTS-----NTNYTNCACVRANISSSIYRGAGGSQAQAL 704
            ||.|.||||:||:||.|.|.||||...||.     :.|.:.|||:
Zfish   461 TSSVSPVCGSNGVTYLSSCFAGCTRAISTGLPAPLSQNLSGCACI-------------------- 505

  Fly   705 SANENFAEVTVVPVATAGPCATP-CRTIY-PFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSF 767
            |...:||  |.||    |.|..| |:..: .||.::...:.:.|..|.|.::|::|:||.|.:|:
Zfish   506 SGYNDFA--TAVP----GKCPRPGCQEAFLTFLCVICGCSMIGAMAQTPSVIILIRTVSPELKSY 564

  Fly   768 ALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLI 832
            |||:.|::.||.|:||.|::||..|||||:.|.:.||.||. ||:||...:|:.|:.:...:|::
Zfish   565 ALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSAECGVKGA-CLLYDNVTYRHLYISMAIVLKIM 628

  Fly   833 ALVIFMVDWWLVRR--RKQLEKMKPLNASDPIIGSIISLDKLFEEKLSGAEPSTAFV 887
            |.:::...|..:||  :|.::.::.......:..|.::||.|.::........|.|:
Zfish   629 AFLLYTTTWHCLRRNYKKYIKNIEGYLTPTEVFSSSMNLDSLGKDSSQSQVNRTKFI 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	248/657 (38%)
		MFS	174..>433	CDD:119392	101/260 (39%)
		MFS	512..>600	CDD:304372	40/87 (46%)
		KAZAL_SLC21	633..684	CDD:238650	25/55 (45%)
slco3a1a	NP_001038653.1	OATP	29..614	CDD:281175	248/657 (38%)
		MFS	35..>265	CDD:119392	98/253 (39%)
		KAZAL_SLC21	449..506	CDD:238650	28/84 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3818
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.800