Protein Alignment Oatp30B and slco4a1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_696263.3
• Gene: slco4a1 / 567865
• ZFINID: ZDB-GENE-060606-4
• Length: 742
• Species: Danio rerio
• Alignment Length: 796
• Identity: 257/796 - (32%)
• Similarity: 380/796 - (47%)
• Gaps: 153/796 - (19%)

  Fly    90 PHA----TSYLAGDQL--------------PSTVGS-GPGGGGPSAVADSVTVKCHSRQASAGKC 135
            ||.    ||:.:..:|              ||.|.| |.|.|.||..|       |:...:.||.
Zfish     2 PHLLNNDTSFSSKQELLVLHNSPLGPSPDTPSPVESQGSGSGSPSGDA-------HTPLHNTGKL 59

  Fly   136 P---ADPEEDF-----DEEQFRSGDCGILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYIN 192
            .   .||....     |.|..    ||.....|..||.|...:..:..|.:...:|..:.:|:||
Zfish    60 GLELTDPPNGLKFVPTDSENL----CGWGALTPRCIQTFNTPRWVLFFLCVASFLQGMIINGFIN 120

  Fly   193 SVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVP 257
            :|||:||:||::.|..:|||||||:|...:.:.||||.|...|.|.|:|.|.::|.:|||||.:|
Zfish   121 TVITSIERRFDLRSYQAGLIASSYDIAACLCLTFVSYFGGTGHKPRWLGWGVLVMALGSLVFALP 185

  Fly   258 HFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGP 322
            |||   .|...:.......:|..                       .||   :.|:..:...:..
Zfish   186 HFT---TPAYQVRVPERMGLCSE-----------------------NHT---ETCVGEEGGLSAY 221

  Fly   323 VLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHM 387
            ..:|:|.|.|.|.|.:||:|||.||:|::|::..:.:|||..|:....||..|:|||.:.|:.:.
Zfish   222 RYVFMLGQFLHGVGATPLYTLGVTYLDENVKSNYAPVYIGIFYTAAIVGPAAGYLLGGFFLNIYT 286

  Fly   388 DSLSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKI--RKSSVVQPVL 450
            : :..|| .:||.:..|||.||.|||..|...|::|:|...:|:.|...::.:  |.|...|  |
Zfish   287 E-IGQTT-ELTPENPLWVGAWWIGFLAGGAAALLIALPILGYPRQLPGSQRYVAMRVSEAHQ--L 347

  Fly   451 PNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTC 515
            .:.|:.|.:                            |..:||.:||:|:|||.|:|||.:|..|
Zfish   348 KDGSQVTAS----------------------------DPQFGKTVKDMPRSMLLLLKNPTFIFLC 384

  Fly   516 LGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGA 580
            |....|..:::|...|.||:||:||||..|:|..:.|.:.||....|.||||.|:|:..|:.:|.
Zfish   385 LAGATEATLIAGMSTFGPKFLESQFSLSASEAATWFGYMVVPAGGGGTFLGGFIIKKLNLRCRGI 449

  Fly   581 VQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTS-------------NKHGSTLEQPFQVN 632
            ::|.::..::.|.. ..:|.:.|.|:.|||.||.||::             :||.|:...  ..|
Zfish   450 IRFCMLCALVSLMA-IFIFLVHCPNVPMAGVTISYYSNVTHNHNSALYLQKDKHNSSFSD--LSN 511

  Fly   633 LTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFSSTSNTN----YTNCACVRANISSSIY 693
            ||.|||.||.||.....||||.:|:.|||||||||::.:.|....    ::.|:||..|||
Zfish   512 LTVACNIGCHCLEESFNPVCGADGVMYFSPCHAGCSSLNHTFGPRGRQVFSGCSCVAGNIS---- 572

  Fly   694 RGAGGSQAQALSANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLR 758
               .|.|        .|||        .|.|.:.|..:..||..||.:........:|.|...||
Zfish   573 ---WGEQ--------GFAE--------EGRCVSSCNHMPAFLTFLFILILFTFLCSIPALTATLR 618

  Fly   759 SVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYV 823
            .|.:.:|||.||:|:::.|..|.||.||.||::||.:|:||:..|||.|. |.:|        :.
Zfish   619 CVPDSQRSFGLGIQWIVVRTLGGIPGPIAFGSVIDISCLLWEEQCGEYGS-CYLY--------HN 674

  Fly   824 GLCASVKLIALVIFMV 839
            ...:...|:|.:|:.|
Zfish   675 SAMSQYSLVAGIIYKV 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	197/606 (33%)
		UhpC	<730..795	CDD:441872	25/64 (39%)
slco4a1	XP_696263.3	MFS	97..618	CDD:475125	197/607 (32%)