Protein Alignment Oatp30B and slco1c1

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_005164528.1
• Gene: slco1c1 / 562772
• ZFINID: ZDB-GENE-041210-50
• Length: 710
• Species: Danio rerio
• Alignment Length: 787
• Identity: 240/787 - (30%)
• Similarity: 377/787 - (47%)
• Gaps: 143/787 - (18%)

  Fly   170 KIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRR 234
            |:|:|.|| .....:|||..|:.|.||.:|:||:|||...|:|..|:||||::.:.||||.|::.
Zfish    47 KMFLVALS-FAYFSKALSGSYMKSTITQLERRFDIPSYLIGVIDGSFEIGNLLVIAFVSYFGAKL 110

  Fly   235 HIPVWIGIGAVIMGIGSLVFMVPHF-----TGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLS 294
            |.|..|.||.::|.:|:.:..:|||     ..|.:..:::.:.:|.:.|.             ||
Zfish   111 HRPKIIAIGCLLMSLGTFLIALPHFIIGRYKFETSIRLSVNSSSSLSPCS-------------LS 162

  Fly   295 SGLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSM 359
            |...:....|.|    .| |.::..:..:.:| |..:|.|.|.:|:..||.:|:|||...|:::.
Zfish   163 SAEPSTSSVPST----GC-EHESRLSMWIYVF-LGNILRGIGETPVQPLGISYIDDHALEENAAF 221

  Fly   360 YIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPGDRRWVGMWWGGFLLCGVILLVV 422
            |||.:.::...|||.|:|||:.....::|  .::..:|||||||.||||.||.|:|:.|.|.|:.
Zfish   222 YIGCVQTISVIGPVFGYLLGSVCAKIYVDIGFVNMESISITPGDARWVGAWWLGYLIAGFITLLS 286

  Fly   423 AVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKV 487
            ||||:..||.|...::::.|.|        ..|.:...|.          |:...:.|:..|
Zfish   287 AVPFWFLPKSLPLPERRLSKYS--------PERNSFIKDS----------ALLEHKYQADEP--- 330

  Fly   488 DTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTG 552
             ..:.:..||...::..|:.||||.:......::...:.|.|.:.|||:|..:....|:||...|
Zfish   331 -ANFLEMAKDFLPTLRSLLGNPVYFLYLCVTIIQFNSLIGMVTYKPKYIEQHYGQSASKANFLMG 394

  Fly   553 SIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFF--LGCDNLKMAGTTIPY 615
            .|.:|...:|:|.||.|:|:|:|...||.:|.|.|::  |..:..|||  :||:|..:||.|:.|
Zfish   395 VINIPAVALGMFSGGVIMKKFKLSIMGAAKFALGTSL--LGYFLSLFFFSMGCENASVAGITMSY 457

  Fly   616 YTSNKHGSTLEQPFQV--NLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGC-TAFSSTSNTN 677
                 :|:  |..|..  :|.|:||..|.|.....:||||.:||||.|||.||| |:..|..:|.
Zfish   458 -----NGT--ESLFMADGSLRASCNAACHCPEKNWDPVCGEDGLTYVSPCLAGCRTSHGSGMDTV 515

  Fly   678 YTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPC--ATPCRTIYPFLILLFF 740
            :..|:|:          |.|..                  .||||.|  ...|..|:|:.:.|..
Zfish   516 FEQCSCI----------GVGNQ------------------TATAGQCNNRESCHRIFPYFLALSV 552

  Fly   741 MT-FLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILW-KSSC 803
            :| |:::....|..|:::|.:..:.:|.|||...:..|....|||||.||.:||:||:.| ...|
Zfish   553 ITSFIISLGGTPGYMLLIRCIKPQLKSLALGFHTLTTRTLAGIPAPIYFGAIIDTTCLKWGHKKC 617

  Fly   804 GEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQLEKMKPLNASDPIIGSIIS 868
            |.:|. |.||:...:|..|:||...::.::..:.::...::||..|.:
Zfish   618 GGRGA-CRIYNTAAYRIAYLGLTLGLRTVSFFLCILGLLVLRRHVQKQ----------------- 664

  Fly   869 LDKLFEEKLSGAEPSTAFVGG---GGELIIPTDILRHSRNDSRTMHMDYCYDKCGRVVTPANTCN 930
                        |.||...||   .|||    ..||...|:|           |.....|.||..
Zfish   665 ------------ERSTMVNGGSAAAGEL----QALRKEENNS-----------CNSEQCPQNTDY 702

  Fly   931 QPQTKSK 937
            .|:.:::
Zfish   703 DPERETR 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	215/662 (32%)
		MFS	174..>433	CDD:119392	96/265 (36%)
		MFS	512..>600	CDD:304372	27/87 (31%)
		KAZAL_SLC21	633..684	CDD:238650	24/51 (47%)
slco1c1	XP_005164528.1	OATP	48..631	CDD:281175	215/662 (32%)
		MFS	50..461	CDD:119392	148/461 (32%)
		KAZAL_SLC21	470..523	CDD:238650	25/62 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810