Protein Alignment Oatp30B and Slco6d1

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_017452073.1
• Gene: Slco6d1 / 367321
• RGDID: 1359388
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 781
• Identity: 191/781 - (24%)
• Similarity: 311/781 - (39%)
• Gaps: 178/781 - (22%)

  Fly   139 PEEDFDEEQF----RSGDCG----ILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVI 195
            |||.....||    ..|..|    :..|    :|||..|..|:....|..|     :.|.|..::
  Rat    50 PEEKMPHSQFSDSLEEGSFGLGPLVFPC----LQRFNNINCFLTAYFLGTM-----AHGMIFGLV 105

  Fly   196 TTIEKRFEIPSSYSGLIASSYEIGNVITVIFVS----YLGSRRHIPVWIGIGAVIMGIGSLVFMV 256
            ....|.:....|.|.|...:...|:.:....||    :.|.|.:...|:.....:.|:.|:||.:
  Rat   106 DQSLKVYVSELSPSKLETLTMGSGDDLAAFLVSLVGAHFGGRGNRVRWMVAACFVTGLASMVFAI 170

  Fly   257 PHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTG 321
            |.|..|    |..:...:|.:|..          |:.::.:..:.:.||   :..|
  Rat   171 PFFNYE----IIKLGTVTDELCIE----------GKKTTKVCERTVIPH---KSTC--------- 209

  Fly   322 PVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFH 386
             :..|...|.|.|..|.|.:.|..:::.|||.|.||.:|:....:..:.|.|:|:|:|.....|.
  Rat   210 -IAFFNFGQFLHGIAGMPFYLLAFSFIFDHVPTCSSGLYLAIADTALSVGYVLGYLVGIRNRMFP 273

  Fly   387 MDSLSSTTISITPGDRRWVG----------MWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIR 441
            :..           |.:.||          .||..:....|......:|...||..| |..::||
  Rat   274 VKE-----------DMKAVGHVQQFRILQRNWWRSYFAVAVFAFCTTLPLSCFPSRL-RGAQQIR 326

  Fly   442 KSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKD------IKDIPQ 500
            .                                    ::|:.||.:|... ||      :|.:..
  Rat   327 L------------------------------------EKSKEPPTIDRRL-KDKEIQPGLKGVLH 354

  Fly   501 SMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFL 565
            ::..|::||:.:........:.:.:.....||||:|::.|.:..:.|:|.||...:|||.||.||
  Rat   355 AIWCLLRNPLVLTQTFCQVTKSLTLKSSGYFLPKFLQSHFLIVPTNASILTGMFVLPGALIGRFL 419

  Fly   566 GGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSNKHGSTLEQPFQ 630
            ||.|:.|.|:..|..::|:::::.|.:..:.:.||..|:....||....|....|.|
  Rat   420 GGYIVDRLQMSTKVVLKFMMVSSFISVVLFLLTFFWSCETAGFAGINDDYDGLGKLG-------- 476

  Fly   631 VNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFSSTSNTN-YTNCACVRANISSSIYR 694
             |.||.||..|.|..::...:||.:...|||.|.|||.|........ |.||:|::..::
  Rat   477 -NFTAPCNEYCGCTMTDYSTICGRDEKQYFSACFAGCRASKPLRKEKAYYNCSCIKEGLT----- 535

  Fly   695 GAGGSQAQALSANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTFLVAS-TQMPLLMIVLR 758
                    |...:..|.:      |.:|.|.|.|.|: |.|...:|...:.:: ..:|..||||:
  Rat   536 --------APDDDGQFFD------AVSGTCNTKCLTL-PLLFAFYFAATVFSNFCSVPSFMIVLK 585

  Fly   759 SVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWK-SSCGEKGGRCLIYDIEKFRY-- 820
            ||.....|.:||:.:.|:|..|.:|..:||.:..|.||..|. :||||| |||.||:.:...:
  Rat   586 SVPASWNSMSLGVTYTIWRFLGSVPDHLLFESTSDYTCNFWDINSCGEK-GRCWIYNKKNLLFTF 649

  Fly   821 -----KYV-------GLC-------------ASVKLIALV-IFMVDWWLVRRRKQLEKMKPLNAS 859
                 |::       |:|             .|..|:.|. |:..|:.:..:.|.|    |::..
  Rat   650 QSTSDKHIEDIKLNKGICDISARSQQGISMQISTGLLCLYGIYRHDYVVKEKNKSL----PIHVK 710

  Fly   860 D 860
            |
  Rat   711 D 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	167/669 (25%)
		MFS	174..>433	CDD:119392	57/272 (21%)
		MFS	512..>600	CDD:304372	25/87 (29%)
		KAZAL_SLC21	633..684	CDD:238650	19/51 (37%)
Slco6d1	XP_017452073.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123298at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820