Protein Alignment Oatp30B and Oatp30B

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_061511392.1
• Gene: Oatp30B / 3291790
• VectorBaseID: AGAMI1_001745
• Length: 1336
• Species: Anopheles gambiae
• Alignment Length: 1271
• Identity: 734/1271 - (57%)
• Similarity: 862/1271 - (67%)
• Gaps: 225/1271 - (17%)

  Fly    38 SSSNGHIANDAGTANRKGHRRQESMYQMTGLYSETNSGDDSSIDAALDHDSQPHATSYLAGDQLP 102
            ::|.|.|  |.|.:.||||||.||||.|||||||..: ||||.|...|.:|:....|........
Mosquito     4 TTSGGTI--DGGNSQRKGHRRNESMYAMTGLYSEAQT-DDSSADIPQDTESESLPMSVNTATTTA 65

  Fly   103 STVGSGPGGGGPSAVADSVTVKCHSRQASAGKCPADPEED------FDEEQFRSGDCGILNCRPY 161
            ||..:     ..:|.||:| :||||||.|: ....|.::.      .:::..|  |||||||||.
Mosquito    66 STTAT-----SATATADTV-IKCHSRQPSS-SVMMDRDKPLPNVLLINDDYMR--DCGILNCRPS 121

  Fly   162 GIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIF 226
            .:|.|||||:||:|||:||.:|||||||||||||||||||||||||.||||||||||||||||||
Mosquito   122 AVQHFARIKVFVLLLSILVTLQQALSSGYINSVITTIEKRFEIPSSLSGLIASSYEIGNVITVIF 186

  Fly   227 VSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLG 291
            |||||||||||||||||||||||||||||:|||||||||||.|.||||||||:...||:|||.||
Mosquito   187 VSYLGSRRHIPVWIGIGAVIMGIGSLVFMLPHFTGEPNPGILIDNKTSDNICRLVSVREQDMGLG 251

  Fly   292 RLSSGLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTES 356
            |||:.|||.||..|.||.||||:.||||.|||:|||:||:|||.||||||||||||||||||.||
Mosquito   252 RLSNSLSNPPLTSHNLRGDNCLKSKASTFGPVILFVIAQILLGGGGSPLFTLGTTYVDDHVRKES 316

  Fly   357 SSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFLLCGVILLV 421
            ||||||.||||.|||||:|||||||||||||||.|.:.|:|.|.|||||||||||||:||::|::
Mosquito   317 SSMYIGAMYSMAAFGPVLGFLLGAYLLSFHMDSFSGSDINIDPDDRRWVGMWWGGFLVCGILLII 381

  Fly   422 VAVPFFSFPKVLAREKKKIR----KSSVVQPVLPNN------SRATVATDEMGKVKKLEIVAVTS 476
            ||||||||||||.|||||||    :...:|.:..||      |:..:|..:..:...|:...:.|
Mosquito   382 VAVPFFSFPKVLTREKKKIRIAEQRLPQLQQLTSNNSSSLPRSQPNLAQQQQQQTGTLQQQPLPS 446

  Fly   477 KEDQSQ---------APPKV-----DTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSG 527
            ::.|.|         |.|:.     |||||||||||||||.|||.||||||||||||||||||||
Mosquito   447 QQQQQQQQTGHGANNAAPQANKTGEDTGYGKDIKDIPQSMWRLVTNPVYIVTCLGACMELMIVSG 511

  Fly   528 FVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICL 592
            ||||||||||||||||||||::|||||||||||||||:|||||||||||||||||||||:|:|||
Mosquito   512 FVVFLPKYLETQFSLGKSQASVFTGSIAVPGACIGIFIGGCILKRFQLKPKGAVQFVLISNLICL 576

  Fly   593 ACYAMLFFLGCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGL 657
            :||.:||||||:||||||||||||.|:.|.   .:||||||||||||||||...:||||||||||
Mosquito   577 SCYGLLFFLGCENLKMAGTTIPYYNSSAHS---VEPFQVNLTAACNFGCECHMYDVEPVCGNNGL 638

  Fly   658 TYFSPCHAGCTAFSSTSNTNYTNCACVRANI-SSSIYRGAGGSQAQALSANENFAEVTVVPVATA 721
            |||||||||||||||:|  ||||||||:||: ::||||||.|:|||||:|:|.||||||||||||
Mosquito   639 TYFSPCHAGCTAFSSSS--NYTNCACVQANVTNNSIYRGAEGTQAQALNAHEAFAEVTVVPVATA 701

  Fly   722 GPCATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPI 786
            |.|.||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||
Mosquito   702 GVCNTPCRTIYPFLILLFFMTFVVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPI 766

  Fly   787 LFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQLE 851
            :|||||||:|:||||:||||||||||||||||||||||||||:|:||||||::|||||||||.|:
Mosquito   767 VFGNLIDSSCLLWKSTCGEKGGRCLIYDIEKFRYKYVGLCASIKIIALVIFIIDWWLVRRRKNLD 831

  Fly   852 KMKPLNASDPIIGSIISLDKLFEEKLSGAEPSTAFVGGGGELIIPTDIL-----------RHSRN 905
            ||.||:.:: ::||||||||||||| |..:.:.| |...|| .|..|.|           ||.||
Mosquito   832 KMNPLSTNE-LVGSIISLDKLFEEK-STLDENIA-VPFNGE-CISGDALADNNKRILVASRHQRN 892

  Fly   906 DSRTMHMDYCYDKCGRVVTPANTCNQP------QTKSKKHFRSASCDVKMIKSFARDHSSSSGPA 964
            ||:|:.::|.||         :..:||      ...::||:||.|||:|:    .|.:|:::...
Mosquito   893 DSKTIQLEYRYD---------DGVHQPYRLPPAAAATRKHYRSNSCDIKI----QRSNSATNREV 944

  Fly   965 DAAGQDAVGASTKYKNLKKF-QAHTRNHSTDLHDP------------------------------ 998
            |....          .||:| :.||||:|.|.::.
Mosquito   945 DFHDW----------KLKRFMRHHTRNNSHDYNNDHHRHQQQQQSQQQTSSSGHLGRWIALQQHH 999

  Fly   999 ----SQP----------IRYIQNQLRPQDCPEEDDDEELTTGCGHF------------------- 1030
                .||          ||||.|.|:|..          ::|..|.
Mosquito  1000 NSAGEQPPSLASGGASNIRYILNHLKPGS----------SSGSEHVKLGYSSSCSGGGAGGGAPT 1054

  Fly  1031 -VKKHSRNHSYDQ--IYMPNN--IRFDAD----FL--------------RHPHSHHNPKKNVNVL 1072
             .|:|:||:||.|  .::|||  ||.|.|    ||              :...||     :|.||
Mosquito  1055 KKKRHTRNYSYGQEFSFLPNNVIIRLDNDIANKFLSSTGALVTGGGSSRKSSFSH-----DVAVL 1114

  Fly  1073 KN----VVSDVG-----KLKN-------SNEIEAGGAGSRGHSRNNSKDLN-TKISSATPASGQV 1120
            ||    .|:..|     ||.|       :.|:|:  ...:||||.:|:||| ..::....|...|
Mosquito  1115 KNNNIGAVAGCGGMSGAKLNNMKHSSNLNEELES--KYGKGHSRTSSRDLNLLNLAPGALAGSGV 1177

  Fly  1121 VTDASTTGL------------SVLRHRRTNSKDLNY 1144
            |..:..:|:            |:|||||||||||.|
Mosquito  1178 VEPSGPSGILGGIKSLIEDSNSILRHRRTNSKDLKY 1213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	467/612 (76%)
		UhpC	<730..795	CDD:441872	62/64 (97%)
Oatp30B	XP_061511392.1	None