Protein Alignment Oatp30B and Slco5a1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_766429.2
• Gene: Slco5a1 / 240726
• MGIID: 2443431
• Length: 850
• Species: Mus musculus
• Alignment Length: 824
• Identity: 280/824 - (33%)
• Similarity: 438/824 - (53%)
• Gaps: 128/824 - (15%)

  Fly   170 KIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRR 234
            :.|:|.:..|..:|..:.|||::|||||||:|:.:.||.|||:.|.::|||::.|:||||.|.|.
Mouse   131 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRG 195

  Fly   235 HIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVN--KTSDNICKSALVRDQDMDLGRLSSGL 297
            ..|:|:.:|.:::.||:.:|.:|||...|.. |..:|  .::|.:|:               :|.
Mouse   196 RRPLWLAVGGLLIAIGAALFALPHFISPPYQ-IQELNASASNDGLCQ---------------NGN 244

  Fly   298 SNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIG 362
            |...|.|....:|:   |..|....|.|||.||:|:|.|.:|::|||.||:||:|:.:::|:|:.
Mouse   245 STAILEPPPCPKDS---GGNSHWIYVALFVCAQVLIGMGSTPIYTLGPTYLDDNVKKDNASLYLA 306

  Fly   363 FMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVPFF 427
            .||.|||.||.||:|||..|:.|::|  ....:.:...|.|::|.||.|||||.:.:.:|..|.|
Mouse   307 IMYVMGALGPAVGYLLGGLLIGFYVD--PRNPVHLDQSDPRFIGNWWSGFLLCAIAMFLVIFPMF 369

  Fly   428 SFPKVL-AREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGY 491
            :|||.| .|.|||.:.|:.|           |..|::.|.|     :.||::...:..|   .|:
Mouse   370 TFPKKLPPRHKKKKKFSADV-----------VIDDDIIKEK-----SNTSEQMNKKVSP---MGF 415

  Fly   492 GKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAV 556
            ||:::|:|::.:|::.|..::...|....|..||:.|:.|:||::|:||.:..|.|:|:||.|.|
Mouse   416 GKNVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIV 480

  Fly   557 PGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSNKH 621
            |.|.:||.|||.|:|:.:|..:.:.:..:|.:.:.|.|::.||.:||:::.:.|..|||.|
Mouse   481 PSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT---- 541

  Fly   622 GSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGC--TAFSSTSNTNYTNCACV 684
            |.:|..|.: |||.:||..|.|...|.|||||::|:|||:||.|||  :...:|...|||.|.||
Mouse   542 GPSLTMPHR-NLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCINSGNLTTGVRNYTECTCV 605

  Fly   685 RANISSSIYRGAGGSQAQ------ALSANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTF 743
            ::.  ..|.....|.::|      ....|||       ..|.:|.|...|.|:.|||:.||.:||
Mouse   606 QSR--QVITPPTVGQRSQLRVVIVKTYLNEN-------GYAVSGKCKRTCNTLIPFLVFLFIVTF 661

  Fly   744 LVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGG 808
            :.|..|...:::.||||.:|||.||||||||:.|...|||.||.||.:||:||:||:..||.:|.
Mouse   662 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGS 726

  Fly   809 RCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQ-LEKMK----PLNASDPIIGSIIS 868
             |..|::..||:.|.||.|.:|.:..:...:.|:.::.::. |::.:    ||:.....:|
Mouse   727 -CWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRCREFPLSTVSEQVG---- 786

  Fly   869 LDKLFEEKLSGAEPSTAFVGGGGELIIPTDILRHSRNDSRTMHMDYCYDKCGRVVTPANTCNQPQ 933
                        :||.|              .::||..|                     |....
Mouse   787 ------------QPSKA--------------EKYSRTTS---------------------CPAFS 804

  Fly   934 TKSKKHFRSA-----SCDVKMIKS-FARDHSSSSGPADAAGQDA 971
            |:.:.|..:|     .|..:.... |:...|||:.|......||
Mouse   805 TQGEVHEETALQKGFPCTTQTYPGPFSEAVSSSADPGQDESPDA 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	216/598 (36%)
		UhpC	<730..795	CDD:441872	35/64 (55%)
Slco5a1	NP_766429.2	MFS_SLCO5_OATP5	131..676	CDD:340962	216/598 (36%)