Protein Alignment Oatp30B and Y70G10A.3

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_499267.1
• Gene: Y70G10A.3 / 190573
• WormBaseID: WBGene00013499
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 760
• Identity: 208/760 - (27%)
• Similarity: 367/760 - (48%)
• Gaps: 108/760 - (14%)

  Fly   138 DPEEDF-----DEEQFRSGDCGILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITT 197
            :|:|:.     ||:......||...|.|..:|.|...|..:|:|.:...:|..:.:......::|
 Worm    11 EPDENLKHKIEDEDDAEKLLCGYGACTPSWLQGFHNAKCLLVVLGICAFIQSFVVNAIFPVGLST 75

  Fly   198 IEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGE 262
            :|:||::.|:::|:|:|.|:...::.|..|.:.|:..|...|||.|.|||.:|||:..:||:..:
 Worm    76 LERRFKMTSTHTGIISSWYDFAVLLVVFPVCHWGNNGHKGRWIGWGGVIMALGSLICALPHWMVD 140

  Fly   263 -PNPGI-AIVNKTSDNICKSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGPVL- 324
             .:|.: .:.|:|....|.:   ||.....|:           ||           :|...|..
 Worm   141 IYHPDVNDLTNQTDFGQCAN---RDDPECAGK-----------PH-----------SSWFNPYFW 180

  Fly   325 LFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMDS 389
            :|:|.|.|.|.|.:|||::||||:|::|..::|.:|:.....:.:||||:|...|.:||:.:.|.
 Worm   181 MFILGQTLHGVGSTPLFSIGTTYMDENVSQKASPVYLAIHAVLTSFGPVIGVFAGGFLLNLYDDF 245

  Fly   390 LSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNS 454
            .....|.:...|.||||.||.||::..:..|::|.|..:|    |||             ||...
 Worm   246 DRVERIPMERSDPRWVGAWWVGFIISSISALMIAFPILAF----ARE-------------LPEAK 293

  Fly   455 RATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGAC 519
            |        .:.|.:....|.:.:..::||        :|:..:|..:.:::.||.::|......
 Worm   294 R--------HRAKDVNQCHVANGDVNAKAP--------RDLMKLPACVWKILSNPTFLVCIFVGI 342

  Fly   520 MELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFV 584
            .|.:|::||..|:||.|||..|...:.|: :..|:.:..|..|:.:||.|:::.:|:..|.::.:
 Worm   343 FESIIINGFAAFMPKILETLLSTNPTLAS-YLSSVVIFAAATGVMVGGTIIRQLKLQVGGMLKMI 406

  Fly   585 LITNVICLACYAMLFFLG----CDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLT 645
            ::.:|     :|:||..|    |...:..|..:.|     ...::|:....::::.||..|.| .
 Worm   407 IVCHV-----FALLFTTGLLSHCPQREFVGINLGY-----EDLSIEKMHDFSISSTCNADCHC-K 460

  Fly   646 SEVEPVCG-NNGLTYFSPCHAGCTAFSS-TSNTNYTNCACVRANISSSIYRGAGGSQAQALSANE 708
            .|..|||. |.|..|:|.||||||..:: ..::.::.|.|:.:|  |:.:....|.:...
 Worm   461 MEWNPVCDRNTGHMYYSACHAGCTGRTTIDGSSQWSGCGCLTSN--STFHNLIHGIKEHP----- 518

  Fly   709 NFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTFLVAS--TQMPLLMIVLRSVSEEERSFALGM 771
                    .|...|.|...|......|::..|:| :|||  :.:|...|:||.|..::|:.|||:
 Worm   519 --------DVLNQGYCHQDCGYREYILMVTLFIT-VVASFASGIPTQQIMLRVVPFDQRTLALGV 574

  Fly   772 QFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVI 836
            .:...||.|:||..||||.:||:.|:.|..||| |...||:||..|..:...||....||::::.
 Worm   575 NWTFVRLLGFIPGGILFGIIIDTACLEWGESCG-KATSCLVYDPFKLSWTITGLAIVCKLLSILA 638

  Fly   837 FMVDWWLVRRRKQLEKMKPLNASD----PIIGSIISLDKLFEEKL 877
            .::. ::..|...|:....:...|    ..:..:::.|:|.|:.:
 Worm   639 TIIG-YMTYRPSDLDNAGSIQTVDSHCHTALHLVVNDDRLPEQAI 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	159/598 (27%)
		UhpC	<730..795	CDD:441872	26/66 (39%)
Y70G10A.3	NP_499267.1	MFS_SLCO4_OATP4	47..561	CDD:340961	159/599 (27%)