Protein Alignment Oatp30B and Y32F6B.1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_505689.2
• Gene: Y32F6B.1 / 179463
• WormBaseID: WBGene00012531
• Length: 760
• Species: Caenorhabditis elegans
• Alignment Length: 844
• Identity: 201/844 - (23%)
• Similarity: 341/844 - (40%)
• Gaps: 223/844 - (26%)

  Fly   167 ARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLG 231
            ::|..|.::...:..: :::...|:.|.:..|||:|:|||..||.:.|:.:...:..|||.||.|
 Worm     4 SKITWFFIVFGTVYFL-ESIGGFYMTSAVVFIEKQFQIPSRLSGTMVSAGDFAYIPVVIFTSYFG 67

  Fly   232 SRRHIPVWIGIGAVIMGIGSLV-----FMVP--------HF-------------TGEPN------ 264
            .:.:...|||.|.:::.|.:.:     |:.|        |.             .|:.|
 Worm    68 GKGNRARWIGAGCILIAIANFMIASSNFLFPVEQANVTTHIPSALAHQIDRDIVNGDVNSTEHLW 132

  Fly   265 -----PGI-----AIVNKTSD-------------------NICKSA--------LVRDQDMDLGR 292
                 |.|     .::|...|                   .|||:.        .:.|..|...|
 Worm   133 LEQIHPLIDPKNQVVMNYEGDEKSDLLQKYVEYCHYHKGSEICKNLEKYIAEKFPITDAKMSNVR 197

  Fly   293 ----LSSGLSNQPL----APH-TLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYV 348
                |..|..:..|    |.| ..::|.      ||.||.::.....|:||.|.:..|:||...:
 Worm   198 AMVALPYGFCHSMLNFVRAQHYACKKDQ------STLGPFMMIFGGLLVLGVGRTMPFSLGLPLM 256

  Fly   349 DDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFL 413
            ||:|:.::..:|..||:.:...|||:|.|:|..|...::|  .:....:||.|..|:|.||.|||
 Worm   257 DDNVKKQNLPLYFSFMFFVKILGPVIGLLVGGQLNKLYVD--FNPPQGLTPLDPMWIGCWWLGFL 319

  Fly   414 LCGVILLVVAVPFFSFPK----VLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKV---KKLEI 471
            :.|.:|...::..:.||.    :.|.|:                      .|:.|||   |:|.:
 Worm   320 IFGTLLFGPSLVLYFFPSDDLDINAPEE----------------------FDDDGKVKPRKRLNL 362

  Fly   472 VAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYL 536
            |....|:|:.......:|...| |.|...::..||||.:::....|..::::...|:.||..|||
 Worm   363 VDRHIKKDEQGNALMPETIMDK-INDFKATIANLVKNKIFVGAMFGRIIDVLAFKGYFVFQAKYL 426

  Fly   537 ETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFF- 600
            |.||.:.:.:...:..|..:.|...|:.||...:|..:|:.:.|..:|    .:|....|::.|
 Worm   427 ELQFGVPQYRIQRYIASTGIVGFACGVILGSLSMKFLKLQGRKAAAWV----AVCSLVAALISFA 487

  Fly   601 ---LGC--------DNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGN 654
               :||        |.:|:.|   |.:.                  .|...|.|..:.:.|||..
 Worm   488 NGTVGCKSVIGQIGDQIKING---PVFD------------------GCRDDCMCEQTPLYPVCDV 531

  Fly   655 NGLTYFSPCHAGCTA----FSSTSNTNYT-------NCACVRANISSSIYRGAGGSQAQALSANE 708
            :|..|:|||||||..    :|...||..|       |||||...:     :....|..:.....|
 Worm   532 SGSAYYSPCHAGCAMGWKNYSIFDNTKATVDTLIFENCACVDNKV-----KEVSRSYCRTEECEE 591

  Fly   709 NFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTFLVAST-----QMPLLMIVLRSVSEEERSFA 768
            .|..                          |||.....:.     .:|.::||||:|..|.||.:
 Worm   592 RFGR--------------------------FFMHQAFGAVFGGLGVVPGMLIVLRAVPPEHRSVS 630

  Fly   769 LGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIA 833
            ||....:..|...:|:||::|.:||.:|:|||.|| :..|.|.:||.::.|.:...:...:::.:
 Worm   631 LGFNGFLVSLLATLPSPIIWGKIIDMSCLLWKKSC-DSSGSCSVYDTDELRVRLHVIYGCLRIFS 694

  Fly   834 LVIFMVDWWLVRRRKQLEKMKP---------------------LNASDPIIGSIISLDKLFEEK 876
            |:..:..|:..|..|.:|:..|                     .:|::.:..:...||:|.:::
 Worm   695 LISDVWVWYWARGLKLIEEETPEDKDKKEEETEKLHSKRKESLRDAAEKVEKTAYELDQLIDQR 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	164/700 (23%)
		UhpC	<730..795	CDD:441872	21/69 (30%)
Y32F6B.1	NP_505689.2	oat	4..706	CDD:273279	193/790 (24%)