Protein Alignment Oatp30B and Slco1a4

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_571981.1
• Gene: Slco1a4 / 170698
• RGDID: 621389
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 705
• Identity: 219/705 - (31%)
• Similarity: 345/705 - (48%)
• Gaps: 142/705 - (20%)

  Fly   161 YGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVI 225
            :|::.||:||:|::.|: ...:.::||..|:||::|.||::|.||:|..|||..|:||||::.:|
  Rat    11 HGVRCFAKIKMFLLALT-CAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLII 74

  Fly   226 FVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDL 290
            ||||.|::.|.|:.||:|..:||:|..:..:|||
  Rat    75 FVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHF------------------------------- 108

  Fly   291 GRLSSGLSNQPLAPHTLREDN---CLEGKASTTGP--------------VLLFVL-AQLLLGCGG 337
              |......:.:.|.:....|   |:|.::.|..|              :.::|| ..::.|.|.
  Rat   109 --LMGQYEYETILPTSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGE 171

  Fly   338 SPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPG 400
            :|:..||.:|::|..::|:|.:|||.:.:....||::|.||.:...:.::|  |:::..::|||.
  Rat   172 TPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPT 236

  Fly   401 DRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGK 465
            |.||||.||.|||:|..:.::.:.|||.|||.|.:|.            |..|...|....|...
  Rat   237 DTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEG------------LQENVDGTENAKEKKH 289

  Fly   466 VKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVV 530
            .||       :||::        .|..||.....:|   |..||:|::..|.:.::.........
  Rat   290 RKK-------AKEEK--------RGITKDFFVFMKS---LSCNPIYMLFILISVLQFNAFINSFT 336

  Fly   531 FLPKYLETQFSLGKSQANI--FTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLA 593
            |:|||||.|:  |||.|.:  ..|...:|..|:|..:||.|:|:|::..|.|.....   .:||:
  Rat   337 FMPKYLEQQY--GKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAF---WLCLS 396

  Fly   594 CYAMLFF---LGCDNLKMAGTTIPY-------YTSNKHGSTLEQPFQVNLTAACNFGCECLTSEV 648
            .|.:.|.   :.|||..:||.|..|       |..||            :.|.||..|.|.|:..
  Rat   397 EYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENK------------VLADCNTRCNCSTNTW 449

  Fly   649 EPVCGNNGLTYFSPCHAGCTAFSST-SNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAE 712
            :||||:|||.|.|.|.|||.....| :|..:.||:|::::.:||
  Rat   450 DPVCGDNGLAYMSACLAGCEKSVGTGTNMVFQNCSCIQSSGNSS--------------------- 493

  Fly   713 VTVVPVATAGP-CATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIF 776
             .|:.:...|| ||   ..:..|||:..|..|:.:...:|..|::||.:..||:|..:|:.....
  Rat   494 -AVLGLCNKGPDCA---NKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCI 554

  Fly   777 RLFGYIPAPILFGNLIDSTCILWKS-SCGEKGGRCLIYDIEKFRYKYVGLCASVK 830
            |:...|||||.||.|||.||:.|.: .|||.|. |.:|||..||..|:||.|:::
  Rat   555 RILAGIPAPIYFGALIDRTCLHWGTLKCGEPGA-CRMYDINSFRRLYLGLPAALR 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	208/681 (31%)
		MFS	174..>433	CDD:119392	86/278 (31%)
		MFS	512..>600	CDD:304372	26/89 (29%)
		KAZAL_SLC21	633..684	CDD:238650	23/51 (45%)
Slco1a4	NP_571981.1	oat	1..623	CDD:273279	219/705 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810