Protein Alignment Oatp30B and slco5a1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_002935370.3
• Gene: slco5a1 / 100492380
• XenbaseID: XB-GENE-480413
• Length: 879
• Species: Xenopus tropicalis
• Alignment Length: 845
• Identity: 282/845 - (33%)
• Similarity: 440/845 - (52%)
• Gaps: 136/845 - (16%)

  Fly    70 SETNSGDD---------SSIDA----ALDHDSQPHA--TSYLAGDQLPSTVGSG------PGGGG 113
            ::||...|         .:|||    :.|..||.||  |......|..|.:|:|      |...|
 Frog    62 TQTNLTQDKKMFLHSFQGNIDAQGRLSSDISSQSHASPTRTAISFQNTSLLGTGYTERIEPNRNG 126

  Fly   114 PSAVADSVTVKCHSRQASAGKCPADPEEDFDEEQFRSGDCGILNCRPYGIQRFARIKIFVVLLSL 178
                         |:|....               :|.....:..|...:......:.|:|.:..
 Frog   127 -------------SKQKGLS---------------QSSTASSIKSRKGVVIALTDSRCFLVCMCF 163

  Fly   179 LVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRRHIPVWIGIG 243
            |..:|..:.|||::|||||||:|:.:.||.|||:.|.::||:::.|:|:||.|.:...|.|:.||
 Frog   164 LTFIQSLMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGSLLVVVFISYFGGKGRRPRWLAIG 228

  Fly   244 AVIMGIGSLVFMVPHFTGEP-----------NPGIAIVNKTS--DNICKSALVRDQDMDLGRLSS 295
            .:::.:|:.:|.:|||...|           |.|:.:...|:  |::..|...|:        |.
 Frog   229 GLLIALGAALFSLPHFISPPYQIQELNASVANEGLCMNGNTTAKDSLESSMCPRE--------SG 285

  Fly   296 GLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMY 360
            |            :|:.|.        |.||:.||:|:|.|.:|::|||.||:||:|:.:::|:|
 Frog   286 G------------KDHSLY--------VALFICAQILIGMGSTPIYTLGPTYLDDNVKKDNASLY 330

  Fly   361 IGFMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVP 425
            :..||.|||.||..|:|||..|:.|::|..|  .|.|...|.|::|.||.|||||.:.:|:|..|
 Frog   331 LAIMYVMGALGPAAGYLLGGVLIGFYVDPRS--IIHIEQSDPRFIGNWWSGFLLCAMAMLLVIFP 393

  Fly   426 FFSFPKVL-AREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDT 489
            .|:|||.| .|::||.:|.        .||....:.|::.|.|       :|.:.::.|.|....
 Frog   394 MFTFPKKLPPRQRKKKKKK--------GNSYDVSSEDDVLKEK-------SSNKSKADANPGPSI 443

  Fly   490 GYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSI 554
            |:||:.||:|::.:|::.|..::...|....|..||:.|:.|:||::|:||.:..|.|:|:||.|
 Frog   444 GFGKNFKDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASSASIYTGLI 508

  Fly   555 AVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSN 619
            .||.|.:||.|||.|:|:.:|..:.:.:..:|...:.|.|::.||.:|||::.:.|..|||.|
 Frog   509 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICCGVSLLCFSTLFIVGCDSINLGGINIPYTT-- 571

  Fly   620 KHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFS--STSNTNYTNCA 682
              |.||....: |||..||..|.|...|.|||||::|:|||:||.|||.:..  |.:..|||.|.
 Frog   572 --GPTLTMTHR-NLTGGCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVSVGNHSVAVRNYTECG 633

  Fly   683 CVRANISSSIYRGAGGSQAQ------ALSANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFM 741
            ||::.  ..|.....|.::|      ....|||       ..|.:|.|...|.|:.||||.||.:
 Frog   634 CVQSR--QVITPPTVGQRSQLRVVIVKTYLNEN-------GYAVSGKCDRTCNTLIPFLIFLFIV 689

  Fly   742 TFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEK 806
            |.:.|..|...:::.||||.|.||.||||||||:.|...|||.||.||.:||:||:||:..||.:
 Frog   690 TLITACAQPSAIIVTLRSVEEGERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGVQ 754

  Fly   807 GGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRK-QLEKMK----PLNASDPIIGSI 866
            |. |..|::..||:.|.||.|.:|.:..:...:.|:.::.:: ||::.:    |::....::.::
 Frog   755 GS-CWEYNVTSFRFVYFGLAAGLKFLGFIFIFLAWYSIKHKEDQLQRRRWRASPISTVSEMVSNV 818

  Fly   867  866
             Frog   819  818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	215/609 (35%)
		UhpC	<730..795	CDD:441872	35/64 (55%)
slco5a1	XP_002935370.3	MFS_SLCO5_OATP5	155..706	CDD:340962	215/609 (35%)