Protein Alignment Oatp30B and slco1e1

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_009299376.1
• Gene: slco1e1 / 100332946
• ZFINID: ZDB-GENE-100818-2
• Length: 695
• Species: Danio rerio
• Alignment Length: 734
• Identity: 225/734 - (30%)
• Similarity: 357/734 - (48%)
• Gaps: 127/734 - (17%)

  Fly   158 CRPYGIQ--RFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGN 220
            |.|...:  |.:.:|||:..|| .....:.|...|:.|.||.||:||::.||..||:..|:|:||
Zfish    19 CSPEAPEEPRCSSLKIFIGALS-FAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGN 82

  Fly   221 VITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPH-FTGEPNPGIAIVNKTSDNICKSALVR 284
            ::.|..||:.|:|.|.|..||:|..:|.|||.:..:|| |.|......||
Zfish    83 LLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMGRYKFDTAI--------------- 132

  Fly   285 DQDMDLGRLSSGLSNQP--LAP---------HTLRE-DN-----CLEGKASTTGPVLLFV-LAQL 331
                      .|.:|:.  :||         |:::. ||     |::...|:   :.::| |...
Zfish   133 ----------QGFANETVVIAPCQYPTNPSEHSIQHIDNTTGTDCVKDPGSS---MWIYVFLGNA 184

  Fly   332 LLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTT 394
            |.|.|.:|:..||.:|:||..:.|:|:.||..:.::...||:.|||||:.....::|  .:|..:
Zfish   185 LRGIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDS 249

  Fly   395 ISITPGDRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVA 459
            :||||.|.||||.||.||.:....|::..|||:..|:.|.::
Zfish   250 VSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQ----------------------- 291

  Fly   460 TDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQ----SMLRLVKNPVYIVTCLGACM 520
                |:.:|    .:.:.:|.::....:.|.:...:.||.:    |:.||:..|.|.:...|..:
Zfish   292 ----GEEEK----EICNTDDANKEHSVLQTTHTMTLADIAKGFLPSLKRLLCTPAYFLLLCGIVL 348

  Fly   521 ELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVL 585
            :.....|.:.|..||:|.||....|:||...|.:.:|...:||||||.::||::|......|...
Zfish   349 KFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKRYKLSVVAGAQLSF 413

  Fly   586 ITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEP 650
            ||:........:.|...|||:.:||.|:.|     :|:......|.:|.:.||..|.|.|||.:|
Zfish   414 ITSFTAFLLLLLHFGTKCDNVPVAGLTVSY-----NGTPYMPSDQRSLESQCNQDCSCSTSEWDP 473

  Fly   651 VCGNNGLTYFSPCHAGCTAFSST-SNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVT 714
            ||.::|:||.|||.|||||.:.. .||.:.||:||   :|.|   .|.|.::.:|..
Zfish   474 VCSDSGITYMSPCLAGCTASTGQGKNTVFHNCSCV---LSPS---PAEGGRSVSLGQ-------- 524

  Fly   715 VVPVATAGPCATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLF 779
             .|..:|  ||   |:...::.:....:|:.:....|..||::|.::.|.:|.|||:|.::.|..
Zfish   525 -CPQGSA--CA---RSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTL 583

  Fly   780 GYIPAPILFGNLIDSTCILW-KSSCGEKGGRCLIYDIEKFRYKYVGL------CASVKLIALVIF 837
            |.|||||.||.||||.|:.| ...||.:|. |.|||...:|..::.|      |:...:||:::
Zfish   584 GGIPAPIYFGALIDSACLKWGLKKCGGRGA-CRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIV- 646

  Fly   838 MVDWWLVRRRKQLEKMKPL 856
                 |:||:...|::|.|
Zfish   647 -----LLRRQFIKEEVKAL 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	210/673 (31%)
		MFS	174..>433	CDD:119392	90/279 (32%)
		MFS	512..>600	CDD:304372	25/87 (29%)
		KAZAL_SLC21	633..684	CDD:238650	26/51 (51%)
slco1e1	XP_009299376.1	OATP	34..622	CDD:281175	210/673 (31%)
		MFS	36..>288	CDD:119392	90/280 (32%)
		KAZAL_SLC21	456..508	CDD:238650	26/51 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910