Protein Alignment Oatp30B and slco2a1

DIOPT Version :9

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_001135668.1
• Gene: slco2a1 / 100216228
• XenbaseID: XB-GENE-5814577
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 714
• Identity: 228/714 - (31%)
• Similarity: 357/714 - (50%)
• Gaps: 121/714 - (16%)

  Fly   155 ILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIG 219
            |..|:. ||  |..||:|||..:|| .:.|.|.|.|..|.:|||||||.:.||.|||::|.:||.
 Frog    15 ITGCKK-GI--FNNIKVFVVCHALL-QLSQLLYSAYFKSCLTTIEKRFGLSSSSSGLLSSIHEIS 75

  Fly   220 NVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEP------NPGIAIVNKTSDNIC 278
            |.:.:|||||.|||.|.|..||:|.:::.:|:.:..||||..|.      |.|    |::...:|
 Frog    76 NAVLIIFVSYFGSRVHRPRVIGVGGLLLALGTFLLTVPHFVSEKYQYTELNSG----NRSQVLLC 136

  Fly   279 KSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGPVL--LFVLAQLLLGCGGSPLF 341
            ..                 .|:..  |...:...|....:..|..:  :.|:.|||.|.|..|:.
 Frog   137 TG-----------------ENRTF--HCKTQGQHLPVTTNNGGSSMWAIMVVGQLLAGIGTVPIQ 182

  Fly   342 TLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMD--SLSSTTISITPGDRRW 404
            ..|.:||||.....:|::||..::::..|||..|:|||:.:|...:|  .::...:.:|..|.||
 Frog   183 PFGISYVDDFAEPNNSALYIAILFAVAVFGPAFGYLLGSVVLRMFVDIGRVNLEHVDLTVADPRW 247

  Fly   405 VGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKL 469
            :|.||.|.|:....|::.::|:|.|||.:.|.:|...:.:|::.: |:
 Frog   248 IGAWWLGLLIASGCLVITSIPYFFFPKQMLRNEKPAPEENVLRKI-PD----------------- 294

  Fly   470 EIVAVTSKEDQSQAPPKVDTGYGKD-IKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLP 533
                           .|.:.|...| ||..|:.:.||:.||::::..|..|....:::....||.
 Frog   295 ---------------VKAEEGSLSDFIKKFPRYVRRLITNPLFLMLVLCQCSFSSVIAALSTFLN 344

  Fly   534 KYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRF----QLKPKGAVQFVLITNVICLAC 594
            ||||.|:|...|.||...|::.:|.|.:|:.:||.|:|||    |:.|:.|:..:|::.::|:.
 Frog   345 KYLEKQYSSSTSYANFLIGAVNLPTAALGMLIGGIIMKRFCISLQIIPRFALAILLLSILLCVP- 408

  Fly   595 YAMLFFLGCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTY 659
               |||:||....:....:.:.||   |:||         :.|...|.|.....:||||:||:.|
 Frog   409 ---LFFMGCSTQALEMGMVEHSTS---GNTL---------STCTSQCACPEYAFQPVCGSNGVEY 458

  Fly   660 FSPCHAGCTAFSSTSNTN---YTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATA 721
            .|||||||.||:.||:..   |.||:|:...      .|.|.:|                    .
 Frog   459 LSPCHAGCRAFNQTSSEKLRMYRNCSCITDT------SGEGTAQ--------------------T 497

  Fly   722 GPCATPC-RTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAP 785
            |.|.|.| ..:.|.:.|:.|...:...|..||.|:|||.|.::|:|||:|:||::.|...::|||
 Frog   498 GSCPTSCSHLLLPVMFLISFAGLIACLTHNPLYMMVLRVVRQDEKSFAIGVQFLLMRFLAWLPAP 562

  Fly   786 ILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQ 849
            .|||.:|||||::|..||....|.|..|:.:..|.:|:||....|::.:::.....|.|.:||:
 Frog   563 ALFGLVIDSTCLVWDRSCSGNRGACRYYNNDLLRNRYLGLQMGYKILGILLLCAIAWKVSKRKE 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	OATP	171..818	CDD:281175	212/665 (32%)
		MFS	174..>433	CDD:119392	90/268 (34%)
		MFS	512..>600	CDD:304372	29/91 (32%)
		KAZAL_SLC21	633..684	CDD:238650	24/53 (45%)
slco2a1	NP_001135668.1	MFS	25..535	CDD:391944	186/608 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X98
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910